Gene Therapy for Skin Fragility Diseases: The New Generation

被引：6
|
作者：
Bilousova, Ganna [1 ]
机构：
[1] Univ Colorado, Sch Med, Charles C Gates Ctr Regenerat Med, Dept Dermatol, Anschutz Med Campus,12800 E 19th Ave,P18-8125, Aurora, CO 80045 USA
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2019年 / 139卷 / 08期
关键词：
D O I：
10.1016/j.jid.2019.04.001
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Ex vivo gene therapy is a promising approach to treat devastating skin fragility diseases. March et al. and Takashima et al. report that programmable nucleases-TALENs and CRISPR/Cas9-can safely and efficiently correct genetic defects in cultured adult skin cells, paving the way for broader clinical applications of gene therapies in dermatology.
引用
收藏
页码：1634 / 1637
页数：4
相关论文
共 50 条
  • [11] Gene therapy of inherited skin diseases like epidermolysis bullosa
    Gache, Y
    Baldeschi, C
    Gagnoux, L
    Spirito, F
    Bouillé, P
    Del Rio, M
    Bruckner-Tuderman, L
    Ortonne, JP
    Meneguzzi, G
    JOURNAL OF GENE MEDICINE, 2003, 5 (03): : S12 - S12
  • [12] Gene therapy gives boy new skin
    Matacic, Catherine
    SCIENCE, 2017, 358 (6364) : 702 - 702
  • [13] Gene therapy for respiratory diseases: A new age?
    Chinet, T
    REVUE DES MALADIES RESPIRATOIRES, 1995, 12 (06) : 515 - 516
  • [14] The New Frontiers of Gene Therapy and Gene Editing in Inflammatory Diseases
    Romano, Alessandro
    Mortellaro, Alessandra
    HUMAN GENE THERAPY, 2024, 35 (7-8) : 219 - 231
  • [15] DISEASES OF SKIN - BASIS OF SKIN THERAPY
    HUNTER, JAA
    BRITISH MEDICAL JOURNAL, 1973, 4 (5889): : 411 - 413
  • [16] Inducible mouse models for inherited skin diseases: implications for gene therapy
    Roop, DR
    JOURNAL OF GENE MEDICINE, 2003, 5 (03): : S11 - S11
  • [17] Impact of a new generation of gene transfer markers on gene therapy
    B Fehse
    Z Li
    UM Schade
    A Uhde
    AR Zander
    Gene Therapy, 1998, 5 : 429 - 430
  • [18] Revertant Mosaicism in Heritable Skin Diseases - Mechanisms of Natural Gene Therapy
    Pasmooij, Anna M. G.
    Jonkman, Marcel F.
    Uitto, Jouni
    DISCOVERY MEDICINE, 2012, 14 (76) : 167 - 179
  • [19] Impact of a new generation of gene transfer markers on gene therapy
    Fehse, B
    Li, Z
    Schade, UM
    Uhde, A
    Zander, AR
    GENE THERAPY, 1998, 5 (04) : 429 - 430
  • [20] Inducible mouse models for inherited skin diseases: implications for gene therapy
    Roop, DR
    EXPERIMENTAL DERMATOLOGY, 2003, 12 (02) : 219 - 220
12345