Gene Therapy for Skin Fragility Diseases: The New Generation

被引：6
|
作者：
Bilousova, Ganna [1 ]
机构：
[1] Univ Colorado, Sch Med, Charles C Gates Ctr Regenerat Med, Dept Dermatol, Anschutz Med Campus,12800 E 19th Ave,P18-8125, Aurora, CO 80045 USA
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2019年 / 139卷 / 08期
关键词：
D O I：
10.1016/j.jid.2019.04.001
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Ex vivo gene therapy is a promising approach to treat devastating skin fragility diseases. March et al. and Takashima et al. report that programmable nucleases-TALENs and CRISPR/Cas9-can safely and efficiently correct genetic defects in cultured adult skin cells, paving the way for broader clinical applications of gene therapies in dermatology.
引用
收藏
页码：1634 / 1637
页数：4
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