Cortical Hyperexcitability in Amyotrophic Lateral Sclerosis C9orf72 Repeats

被引：11
|
作者：
Wainger, Brian J. [1 ,2 ]
Cudkowicz, Merit E. [1 ]
机构：
[1] Massachusetts Gen Hosp, Dept Neurol, Charlestown, MA 02129 USA
[2] Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Charlestown, MA 02129 USA
来源：
JAMA NEUROLOGY | 2015年 / 72卷 / 11期
关键词：
SPINAL MOTONEURONS; EXCITABILITY; STIMULATION; LESSONS; DISEASE; MODEL;
D O I：
10.1001/jamaneurol.2015.2197
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：1235 / 1236
页数：2
相关论文
共 50 条
  • [41] Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
    Zongbing Hao
    Rui Wang
    Haigang Ren
    Guanghui Wang
    NeuroscienceBulletin, 2020, 36 (09) : 1057 - 1070
  • [42] Metabolic changes specific of C9ORF72 genetic lesion in Amyotrophic Lateral Sclerosis
    Pagani, M. M.
    Chio, A.
    Valentini, M.
    Calvo, A.
    Moglia, C.
    Montuschi, A.
    Nobili, F.
    Fania, P.
    Cistaro, A.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 39 : S217 - S217
  • [43] The Association between C9orf72 Repeats and Risk of Alzheimer's Disease and Amyotrophic Lateral Sclerosis: A Meta-Analysis
    Shu, Li
    Sun, Qiying
    Zhang, Yuan
    Xu, Qian
    Guo, Jifeng
    Yan, Xinxiang
    Tang, Beisha
    PARKINSONS DISEASE, 2016, 2016
  • [44] C9ORF72 GGGGCC Expanded Repeats Produce Splicing Dysregulation which Correlates with Disease Severity in Amyotrophic Lateral Sclerosis
    Cooper-Knock, Johnathan
    Bury, Joanna J.
    Heath, Paul R.
    Wyles, Matthew
    Higginbottom, Adrian
    Gelsthorpe, Catherine
    Highley, J. Robin
    Hautbergue, Guillaume
    Rattray, Magnus
    Kirby, Janine
    Shaw, Pamela J.
    PLOS ONE, 2015, 10 (05):
  • [45] Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72
    Ismail, Azza
    Cooper-Knock, Johnathan
    Highley, J. Robin
    Milano, Antonio
    Kirby, Janine
    Goodall, Emily
    Lowe, James
    Scott, Ian
    Constantinescu, Cris S.
    Walters, Stephen J.
    Price, Sian
    McDermott, Christopher J.
    Sawcer, Stephen
    Compston, D. Alastair S.
    Sharrack, Basil
    Shaw, Pamela J.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2013, 84 (01): : 79 - 87
  • [46] Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion
    Waite, Adrian J.
    Baeumer, Dirk
    East, Simon
    Neal, James
    Morris, Huw R.
    Ansorge, Olaf
    Blake, Derek J.
    NEUROBIOLOGY OF AGING, 2014, 35 (07) : 1779.e5 - 1779.e13
  • [47] Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
    Jie Jiang
    John Ravits
    Neurotherapeutics, 2019, 16 : 1115 - 1132
  • [48] Intermediate repeat expansion length in C9orf72 may be pathological in amyotrophic lateral sclerosis
    Byrne, Susan
    Heverin, Mark
    Elamin, Marwa
    Walsh, Cathal
    Hardiman, Orla
    AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2014, 15 (1-2) : 148 - 150
  • [49] Analysis of C9orf72 in patients with frontotemporal dementia and amyotrophic lateral sclerosis from Argentina
    Itzcovich, Tatiana
    Xi, Zhengrui
    Martinetto, Horacio
    Chrem-Mendez, Patricio
    Julieta Russo, Maria
    de Ambrosi, Bruno
    Uchitel, Osvaldo D.
    Nogues, Martin
    Silva, Emanuel
    Rojas, Galeno
    Bagnatti, Pablo
    Amengual, Alejandra
    Campos, Jorge
    Rogaeva, Ekaterina
    St George-Hyslop, Peter
    Allegri, Ricardo
    Sevlever, Gustavo
    Surace, Ezequiel I.
    NEUROBIOLOGY OF AGING, 2016, 40 : 192.e13 - 192.e15
  • [50] How can an understanding of the C9orf72 gene translate into amyotrophic lateral sclerosis therapies?
    Berth, Sarah H.
    Lloyd, Thomas E.
    EXPERT REVIEW OF NEUROTHERAPEUTICS, 2019, 19 (10) : 895 - 897
12345