Induction of non-protective autophagy by radiation in tumor cells: Implications for autophagy inhibition as a therapeutic strategy

被引:0
|
作者
Chakradeo, Shweta [1 ]
Sharma, Khushboo [1 ]
Alhaddad, Aisha [1 ]
Bakhshwin, Duaa [1 ]
Le, Ngoc [1 ]
Harada, Hisashi [1 ]
Yeudall, W. Andrew [1 ]
Torti, Suzy [2 ]
Torti, Frank [2 ]
Gewirtz, David [1 ]
机构
[1] VCU, Richmond, VA USA
[2] Univ Connecticut, Farmington, CT USA
关键词
D O I
10.1158/1538-7445.AM2015-998
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
998
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Inhibition of autophagy as a therapeutic strategy of iron-induced brain injury after hemorrhage
    Chen, Chiu-Wei
    Chen, Tzu-Yin
    Tsai, Ke-Li
    Lin, Chih-Lung
    Yokoyama, Kazunari K.
    Lee, Wen-Sen
    Chiueh, Chuang Chin
    Hsu, Chin
    AUTOPHAGY, 2012, 8 (10) : 1510 - 1520
  • [42] A Novel Anticancer Therapeutic Strategy to Target Autophagy Accelerates Radiation-Associated Atherosclerosis
    Yuan, Ruosen
    Sun, Zhe
    Cai, Jiali
    Yang, Xiaoxiao
    Zhang, Weifeng
    Wu, Caizhe
    Shen, Yejiao
    Yin, Anwen
    Wang, Xia
    Cai, Xuwei
    Fu, Xiaolong
    Shen, Linghong
    He, Ben
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2021, 109 (02): : 540 - 552
  • [43] Recent Advances in the Roles of Autophagy and Autophagy Proteins in Host Cells During Toxoplasma gondii Infection and Potential Therapeutic Implications
    Subauste, Carlos S.
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
  • [44] Neural stem cells neuroprotection by simvastatin via autophagy induction and apoptosis inhibition
    Varmazyar, R.
    Noori-Zadeh, A.
    Abbaszadeh, H. A.
    Hamidabadi, Ghasemi H.
    Rajaei, F.
    Darabi, S.
    Rezaie, M. J.
    Abdollahifar, M. A.
    Zafari, F.
    Bakhtiyari, S.
    BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, 2019, 120 (10): : 744 - 751
  • [45] Protective autophagy elicited by RAF®MEK®ERK inhibition suggests a treatment strategy for pancreatic cancer
    Kinsey, Conan G.
    Camolotto, Soledad A.
    Boespflug, Amelie M.
    Guillen, Katrin P.
    Foth, Mona
    Truong, Amanda
    Schuman, Sophia S.
    Shea, Jill E.
    Seipp, Michael T.
    Yap, Jeffrey T.
    Burrell, Lance D.
    Lum, David H.
    Whisenant, Jonathan R.
    Gilcrease, G. Weldon
    Cavalieri, Courtney C.
    Rehbein, Kaitrin M.
    Cutler, Stephanie L.
    Affolter, Kajsa E.
    Welm, Alana L.
    Welm, Bryan E.
    Scaife, Courtney L.
    Snyder, Eric L.
    McMahon, Martin
    CANCER RESEARCH, 2019, 79 (13)
  • [46] Crosstalk between autophagy and metabolic regulation of (CAR) T cells: therapeutic implications
    Meymandi, Ahmad Reza Panahi
    Akbari, Behnia
    Soltantoyeh, Tahereh
    Hadjati, Jamshid
    Klionsky, Daniel J.
    Badie, Behnam
    Mirzaei, Hamid Reza
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [47] Hyperphosphatemia induces protective autophagy in endothelial cells through the inhibition of Akt/mTOR signaling
    Hsu, Yu-Juei
    Hsu, Shih-Che
    Huang, Shih-Ming
    Lee, Herng-Sheng
    Lin, Shih-Hua
    Tsai, Chien-Sung
    Shih, Chun-Che
    Lin, Chih-Yuan
    JOURNAL OF VASCULAR SURGERY, 2015, 62 (01) : 210 - U384
  • [48] Synergy of Tumor Microenvironment Remodeling and Autophagy Inhibition to Sensitize Radiation for Bladder Cancer Treatment
    Lin, Tingsheng
    Zhang, Qing
    Yuan, Ahu
    Wang, Baojun
    Zhang, Feifei
    Ding, Yuanzhen
    Cao, Wenmin
    Chen, Wei
    Guo, Hongqian
    THERANOSTICS, 2020, 10 (17): : 7683 - 7696
  • [49] Combining radiation with autophagy inhibition enhances suppression of tumor growth and angiogenesis in esophageal cancer
    Chen, Yongshun
    Li, Xiaohong
    Guo, Leiming
    Wu, Xiaoyuan
    He, Chunyu
    Zhang, Song
    Xiao, Yanjing
    Yang, Yuanyuan
    Hao, Daxuan
    MOLECULAR MEDICINE REPORTS, 2015, 12 (02) : 1645 - 1652
  • [50] How Tumor Cells Choose Between Epithelial-Mesenchymal Transition and Autophagy to Resist Stress-Therapeutic Implications
    Marcucci, Fabrizio
    Rumio, Cristiano
    FRONTIERS IN PHARMACOLOGY, 2018, 9