Stevia Genus: Phytochemistry and Biological Activities Update

被引：19
|
作者：
Borgo, Jimena [1 ,2 ,3 ]
Laurella, Laura C. [1 ,2 ]
Martini, Florencia [1 ,3 ]
Catalan, Cesar A. N. [4 ]
Sulsen, Valeria P. [1 ,2 ,3 ]
机构：
[1] Univ Buenos Aires, CONICET, Inst Quim & Metabol Farmaco IQUIMEFA, RA-1113 Buenos Aires, DF, Argentina
[2] Univ Buenos Aires, Fac Farm & Bioquim, Catedra Farmacognosia, RA-1113 Buenos Aires, DF, Argentina
[3] Univ Buenos Aires, Fac Farm & Bioquim, Catedra Quim Med, RA-1113 Buenos Aires, DF, Argentina
[4] Univ Nacl Tucuman, Fac Bioquim Quim & Farm, Inst Quim Organ, Ayacucho 471,T4000INI, RA-4000 San Miguel De Tucuman, Tucuman, Argentina
来源：
MOLECULES | 2021年 / 26卷 / 09期
关键词：
Stevia; sesquiterpene lactones; diterpenes; flavonoids; biological activity; NF-KAPPA-B; JAPONICUM VAR. MAACKII; SESQUITERPENE LACTONES INHIBITION; ARTEMISIA-PRINCEPS PAMPANINI; CELL-CYCLE ARREST; IN-VITRO; ALPHA-GLUCOSIDASE; INDUCED INFLAMMATION; NATURAL FLAVONE; DOWN-REGULATION;
D O I：
10.3390/molecules26092733
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The Stevia genus (Asteraceae) comprises around 230 species, distributed from the southern United States to the South American Andean region. Stevia rebaudiana, a Paraguayan herb that produces an intensely sweet diterpene glycoside called stevioside, is the most relevant member of this genus. Apart from S. rebaudiana, many other species belonging to the Stevia genus are considered medicinal and have been popularly used to treat different ailments. The members from this genus produce sesquiterpene lactones, diterpenes, longipinanes, and flavonoids as the main types of phytochemicals. Many pharmacological activities have been described for Stevia extracts and isolated compounds, antioxidant, antiparasitic, antiviral, anti-inflammatory, and antiproliferative activities being the most frequently mentioned. This review aims to present an update of the Stevia genus covering ethnobotanical aspects and traditional uses, phytochemistry, and biological activities of the extracts and isolated compounds.
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收藏
页数：45
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