Successful Triple Combination Immunosuppressive Therapy with Prednisolone, Cyclosporine, and Mycophenolate Mofetil to Treat Recurrent Giant Cell Myocarditis

被引：8

作者：

Akita, Tomomi ^{[1
]}

Mori, Shumpei ^{[1
]}

Onishi, Akira ^{[2
]}

Hara, Shigeo ^{[3
]}

Yamada, Haruhi ^{[1
]}

Nagasawa, Akira ^{[1
]}

Imada, Hiroshi ^{[1
]}

Shimoura, Hiroyuki ^{[1
]}

Ooka, Junichi ^{[1
]}

Tanaka, Hidekazu ^{[1
]}

Hirata, Ken-ichi ^{[1
]}

机构：

[1] Kobe Univ, Grad Sch Med, Dept Internal Med, Div Cardiovasc Med, Kobe, Hyogo, Japan

[2] Kobe Univ, Grad Sch Med, Dept Rheumatol & Clin Immunol, Kobe, Hyogo, Japan

[3] Kobe City Med Ctr Gen Hosp, Dept Diagnost Pathol, Kobe, Hyogo, Japan

来源：

INTERNAL MEDICINE | 2019年 / 58卷 / 14期

关键词：

Cyclosporine; giant cell myocarditis; mycophenolate mofetil; prednisolone; recurrence; DIAGNOSIS;

D O I：

10.2169/internalmedicine.2471-18

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 59-year-old man with a history of giant cell myocarditis was admitted to our hospital with recurrent giant cell myocarditis triggered by a 1 mg/day taper in his prednisolone dose. During the initial episode, he had undergone rescue implantation of a temporary left ventricular assist device followed by the administration of dual immunosuppressive therapy with prednisolone and concomitant cyclosporine. Triple combination immunosuppressive therapy maintained with additional mycophenolate mofetil successfully controlled recurrent myocarditis, enabled a reduction in the prednisolone dose, and achieved the functional recovery of the left ventricle.

引用

页码：2035 / 2039

页数：5

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