Prevalence of amebiasis in inflammatory bowel disease in University Clinical Hospital Mostar

被引:8
|
作者
Babic, Emil [1 ]
Bevanda, Milenko [1 ]
Mimica, Mladen [1 ]
Karin, Maja [1 ]
Volaric, Mile [1 ]
Bogut, Ante [1 ]
Barisic, Tatjana [2 ]
Pravdic, Danijel [1 ]
Sutalo, Nikica [3 ]
机构
[1] Univ Mostar Clin Hosp, Dept Gastroenterol & Hepatol, Bijeli Brijeg Bb, Mostar 88000, Bosnia & Herceg
[2] Univ Mostar Clin Hosp, Dept Ginecol, Bijeli Brijeg Bb, Mostar 88000, Bosnia & Herceg
[3] Univ Mostar Clin Hosp, Dept Abdominal Surg, Bijeli Brijeg Bb, Mostar 88000, Bosnia & Herceg
来源
SPRINGERPLUS | 2016年 / 5卷
关键词
Amebiasis; Inflammatory bowel disease; Prevalence; Immune response; Inflammation; ENTAMOEBA-HISTOLYTICA; PROTEINASE; DISPAR; COLITIS;
D O I
10.1186/s40064-016-3261-7
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Aim: To explore the prevalence of amebiasis in inflammatory bowel disease (IBD), Crohn's disease and ulcerative colitis, in patients in Clinical hospital Mostar (Bosnia and Herzegovina, region of Herzegovina). Methods: In this study, Entamoeba histolytica/dispar prevalence was investigated in fresh faeces by native microscopy and immunochromatographic rapid assay "RIDA (R) QUICK Entamoeba test", in 119 cases of new found IBD patients, 84 of ulcerative colitis and 35 of Crohn's disease and in control group who had also 119 patients who didn't have any gastrointestinal complaints. IBD diagnosis was established by standard diagnostic procedures (anamnesis, clinical manifestations, laboratory, endoscopy and biopsy). Results: Entamoeba histolytica/dispar were found in 19 (16.0 %) of a total of 119 cases, 12 (14.3 %) of the 84 patients with ulcerative colitis and 7 (20.0 %) of the 35 patients with Crohn's disease. As for the 119 patients in the control group who had not any gastrointestinal complaints, 2 (1.7 %) patients were found to have E. histolytica/dispar in their faeces. Amoeba prevalence in the patient group was determined to be significantly higher in group with Crohn's disease, ulcerative colitis and IBD total than in the control group (p < 0.001). Conclusion: Ameba infections in patients with Crohn's disease and ulcerative colitis, have a greater prevalence compared to the normal population.
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页数:4
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