On the uniqueness of the positive solution of an integral equation which appears in epidemiological models

被引:13
|
作者
Lopez, LF [1 ]
Coutinho, FAB [1 ]
机构
[1] Univ Sao Paulo, Sch Med, Discipline, Discipline Med Informat, BR-01246903 Sao Paulo, Brazil
关键词
epidemiology; functional analysis; integral equations; mathematical models;
D O I
10.1007/s002850050178
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In this paper, we show that the positive solution of a nonlinear integral equation which appears in classical SIR epidemiological models is unique. The demonstration of this fact is necessary to justify the correctness of any approximate or numerical solution. The SIR epidemiological model is used only for simplicity. In fact, the methods used can be easily extended to prove the existence and uniqueness of the more involved integral equations that appear when more biological realities are considered. Thus the inclusion of a latent class (SLIR models) and models incorporating variability in the infectiousness with duration of the infection and spatial distribution lead to integral equations to which the results derived in this paper apply immediately.
引用
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页码:199 / 228
页数:30
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