The purpose of this study was to explore the affective qualities which influence subjects' aesthetic preferences. The Stepwise regression analysis was performed to explore what affective meanings influenced subjects' aesthetic preferences. The aesthetic preference was regarded as a dependent variable; the 11 affective meanings found in Huang's study were independent variables. The result showed that 6 adjective pairs: "exquisite", "original", "strong", "childlike", "intense" and "pure" entered the model, called HiSPA affective meanings. Besides, the affective meaning, "exquisite", was the most important affective quality in judgment of aesthetic preferences. It implied that designers had to create the interactive interfaces with an "exquisite" affective quality to please users' aesthetic affects.