On-Chip Fragment-Based Approach for Discovery of High-Affinity Bivalent Inhibitors

被引：7
|
作者：
Miyazaki, Isao
Simizu, Siro
Ishida, Keisuke
Osada, Hiroyuki [1 ]
机构：
[1] RIKEN, Antibiot Lab, Wako, Saitama 3510198, Japan
来源：
CHEMBIOCHEM | 2009年 / 10卷 / 05期
关键词：
fragment combination array; immobilization; inhibitors; photochemistry; structure-activity relationships; SMALL-MOLECULE MICROARRAYS; CARBONIC-ANHYDRASE-II; LIGAND DISCOVERY; LEAD DISCOVERY; BINDING; LIBRARIES; PRODUCTS; PLATFORM; DESIGN; ARRAYS;
D O I：
10.1002/cbic.200800704
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：838 / 843
页数：6
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