Multivalent dendrons for high-affinity adhesion of proteins to DNA

被引：61
|
作者：
Kostiainen, Mauri A.
Szilvay, Geza R.
Smith, David K.
Linder, Markus B.
Ikkala, Olli
机构：
[1] Aalto Univ, Dept Engn Phys & Math, Espoo 02015, Finland
[2] Aalto Univ, Ctr New Mat, Espoo 02015, Finland
[3] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England
[4] Univ Helsinki, Inst Biotechnol, Res Program Struct Biol & Biophys, FIN-00014 Helsinki, Finland
[5] VTT Biotechnol, FIN-02044 Helsinki, Finland
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 21期
关键词：
dendrimers; DNA; multivalency; protein modifications; self-assembly;
D O I：
10.1002/anie.200504540
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) Strength in numbers: Multivalent dendrons that have an N-maleimido group at the focal point can be used to construct monodisperse one-to-one protein-dendron conjugates. The second generation polyamine dendron with spermine surface groups clearly imparts its high-affinity DNA binding to a protein of choice. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：3538 / 3542
页数：5
相关论文
共 50 条
  • [31] Reversible, High-Affinity Surface Capturing of Proteins Directed by Supramolecular Assembly
    Di Palma, Giuseppe
    Kotowska, Anna M.
    Hart, Lewis R.
    Scurr, David J.
    Rawson, Frankie J.
    Tommasone, Stefano
    Mendes, Paula M.
    ACS APPLIED MATERIALS & INTERFACES, 2019, 11 (09) : 8937 - 8944
  • [32] Conformation-Dependent High-Affinity Monoclonal Antibodies to Prion Proteins
    Stanker, Larry H.
    Serban, Ana V.
    Cleveland, Elisa
    Hnasko, Robert
    Lemus, Azucena
    Safar, Jiri
    DeArmond, Stephen J.
    Prusiner, Stanley B.
    JOURNAL OF IMMUNOLOGY, 2010, 185 (01): : 729 - 737
  • [33] Ascorbate-induced high-affinity binding of copper to cytosolic proteins
    Ohta, Y
    Shiraishi, N
    Inai, Y
    Sook, I
    Lee, M
    Iwahashi, H
    Nishikimi, M
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 287 (04) : 888 - 894
  • [34] High-affinity capture of proteins by diamond nanoparticles for mass spectrometric analysis
    Kong, XL
    Huang, LCL
    Hsu, CM
    Chen, WH
    Han, CC
    Chang, HC
    ANALYTICAL CHEMISTRY, 2005, 77 (01) : 259 - 265
  • [35] Design of high-affinity S100-target hybrid proteins
    Rezvanpour, Atoosa
    Phillips, Jeremy M.
    Shaw, Gary S.
    PROTEIN SCIENCE, 2009, 18 (12) : 2528 - 2536
  • [36] Synergistic effect of high-affinity binding and flow preconditioning on endothelial cell adhesion
    Mathur, AB
    Truskey, GA
    Reichert, WM
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2003, 64A (01) : 155 - 163
  • [37] SELECTING HIGH-AFFINITY BINDING-PROTEINS BY MONOVALENT PHAGE DISPLAY
    LOWMAN, HB
    BASS, SH
    SIMPSON, N
    WELLS, JA
    BIOCHEMISTRY, 1991, 30 (45) : 10832 - 10838
  • [38] PHOTOAFFINITY-LABELING OF HIGH-AFFINITY DOPAMINE BINDING-PROTEINS
    ROSS, GM
    MCCARRY, BE
    MISHRA, RK
    FEDERATION PROCEEDINGS, 1986, 45 (03) : 564 - 564
  • [39] HIGH-AFFINITY CALCIUM-BINDING PROTEINS IN ESCHERICHIA-COLI
    HARMON, AC
    PRASHER, D
    CORMIER, MJ
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 127 (01) : 31 - 36
  • [40] Development of a novel strategy for engineering high-affinity proteins by yeast display
    Richman, S. A.
    Healan, S. J.
    Weber, K. S.
    Donermeyer, D. L.
    Dossett, M. L.
    Greenberg, P. D.
    Allen, P. M.
    Kranz, D. M.
    PROTEIN ENGINEERING DESIGN & SELECTION, 2006, 19 (06): : 255 - 264
12345