Porous silicon with deposited iron oxide as vehicle for magnetically guided drug delivery

被引:0
|
作者
Rumpf, K. [1 ]
Granitzer, P. [1 ]
Tian, Y. [2 ]
Coffer, J. [2 ]
Akkaraju, G.
Poelt, P. [3 ]
Michor, H. [4 ]
机构
[1] Karl Franzens Univ Graz, Inst Phys, A-8010 Graz, Austria
[2] Texas Christian Univ, Dept Chem, Ft Worth, TX 76129 USA
[3] Texas Christian Univ, Dept Biol, Ft Worth, TX 76129 USA
[4] Vienna Univ Technol, Inst Solid State Phys, A-1040 Vienna, Austria
关键词
CELLULAR-ASSOCIATION;
D O I
10.1149/05832.0133ecst
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
Due to the fact that both materials porous silicon as well as iron oxide nanoparticles are biocompatible and porous silicon can be functionalized easily to attach therapeutic nucleotides the aim is to create a cytocompatible arrangement to promote magnetically guided delivery into targeted cells. Furthermore porous silicon dissolves in body fluid dependent on the porosity which increases the possible applications. Within the frame of this work the field and temperature dependent magnetic properties of the nanocomposite have been investigated as well as its cytocompatibility according to the porous silicon morphology and the iron oxide particle size.
引用
收藏
页码:133 / 137
页数:5
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