Effect of Silver Nanoparticles toward DNA via Formation of Reactive Oxygen Species

被引：0

作者：

Nemcekova, Katarina ^{[1
]}

Sochr, Jozef ^{[1
]}

Labuda, Jan ^{[1
]}

机构：

[1] Slovak Univ Technol Bratislava, Fac Chem & Food Technol, Inst Analyt Chem, Radlinskeho 9, Bratislava 81237, Slovakia

来源：

PROCEEDINGS OF INTERNATIONAL CONFERENCE MODERN ELECTROCHEMICAL METHODS XXXIX | 2019年

关键词：

Silver nanoparticles; Reactive oxygen species; DNA oxidative stress; Biosensing voltammetry; Spectrophotometry;

D O I：

暂无

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

Nowadays, silver nanoparticles (AgNPs) are commonly utilized materials in medicine, cosmetic or clothing industry due to their antibacterial and antimicrobial properties. However, their potential activity accompanied with environmental and health risks has been poorly revealed. The oxidation stress of biomolecules induced by AgNPs via the formation of reactive oxygen species (ROS) in considered as the main mechanism of their toxicity. The effective evaluation of oxidative damage to DNA represents interesting matter of these days. For this reason, a rapid and reliable detection of DNA degradation was performed using electrochemical biosensing approaches.

引用

页码：163 / 166

页数：4

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