Iridium-Catalyzed Reactions of Trifluoromethylated Compounds with Alkenes: A Csp3-H Bond Activation α to the Trifluoromethyl Group

被引：39
|
作者：
Guo, Yong [1 ]
Zhao, Xiaming [1 ]
Zhang, Dazhi [1 ]
Murahashi, Shun-Ichi [1 ]
机构：
[1] Okayama Univ Sci, Dept Chem, Okayama 7000005, Japan
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 11期
关键词：
alkenes; C H activation; fluorides; iridium; ruthenium; C-F BONDS; CROSS-COUPLING REACTION; GRIGNARD-REAGENTS; NUCLEOPHILIC TRIFLUOROMETHYLATION; PERFLUOROALKYL-COMPLEXES; FLUOROALKYL-COMPLEXES; ELECTRONIC-PROPERTIES; HYDRIDE COMPLEXES; ARYL FLUORIDES; LEWIS-ACID;
D O I：
10.1002/anie.200805852
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Catalytic convenience: The use of iridium or ruthenium catalysts for Csp3-H bond activation has led to the addition reaction of trifluoromethylated compounds to alkenes (see scheme). This atom-economical reaction occurs under neutral reaction conditions and without the formation of undesired defluorinated byproducts, even at high temperature. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：2047 / 2049
页数：3
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