Total synthesis of naamine C and pyronaamidine, antitumor marine imidazole alkaloids

被引：19
|
作者：
Nakamura, S [1 ]
Kawasaki, I [1 ]
Kunimura, M [1 ]
Matsui, M [1 ]
Noma, Y [1 ]
Yamashita, M [1 ]
Ohta, S [1 ]
机构：
[1] Kyoto Pharmaceut Univ, Misasagi Yamashina Ku, Kyoto 6078414, Japan
来源：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2002年 / 08期
关键词：
D O I：
10.1039/b200845a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first total synthesis of naamine C and pyronaamidine, highly substituted and cytotoxic imidazole marine alkaloids of a certain kind of sponge, was achieved through an eight-step reaction starting from 1-methyl-2-phenylthio-1H-imidazole.
引用
收藏
页码：1061 / 1066
页数：6
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