The effect of tocopheryl phosphates on atherosclerosis progression in rabbits fed with a high cholesterol diet

被引：46
|
作者：
Negis, Yesim
Aytan, Nurgul
Ozer, Nesrin
Ogru, Esra
Libinaki, Roksan
Gianello, Robert
Azzi, Angelo
Zingg, Jean-Marc
机构：
[1] Univ Bern, Inst Biochem & Mol Biol, Bern, Switzerland
[2] Marmara Univ, Fac Med, Dept Biochem, TR-81326 Istanbul, Turkey
[3] Phosphagen Ltd, Melbourne, Vic, Australia
[4] Monash Univ, Dept Biochem & Mol Biol, Clayton, Vic 3800, Australia
来源：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 2006年 / 450卷 / 01期
关键词：
tocopherol; antioxidants; atherosclerosis; tocopheryl phosphate;
D O I：
10.1016/j.abb.2006.02.027
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The effect of tocopheryl phosphate on atherosclerosis progression has been studied in rabbits, fed with a 2% cholesterol diet and compared with an equivalent amount of alpha-tocopheryl acetate. The results show that the atherosclerotic-preventing effect of the phosphate derivative was more pronounced than that of the acetate derivative. alpha-Tocopheryl phosphate was also more potent in diminishing the expression of CD36 than the acetate derivative. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码：63 / 66
页数：4
相关论文
共 50 条
  • [1] PROGRESSION OF INDUCED AORTIC ATHEROSCLEROSIS IN RABBITS FED A HIGH CHOLESTEROL DIET
    RESTORI, G
    BOIARDI, L
    BARBAGALLO, M
    NOVO, S
    PASSERI, M
    STRANO, A
    INTERNATIONAL ANGIOLOGY, 1990, 9 (04) : 263 - 265
  • [2] EFFECT OF FISH OIL ON ATHEROSCLEROSIS IN RABBITS FED A HIGH CHOLESTEROL DIET
    HALLERMAYER, G
    ANTON, H
    BRUCKMAIER, C
    MILOTZKE, W
    SCHIEROK, HJ
    ARTERIOSCLEROSIS, 1990, 10 (05): : A792 - A792
  • [3] VERAPAMIL AND DIET HALT PROGRESSION OF ATHEROSCLEROSIS IN CHOLESTEROL-FED RABBITS
    SIEVERS, R
    RASHID, T
    GARRETT, J
    BLUMLEIN, S
    PARMLEY, W
    ARTERIOSCLEROSIS, 1985, 5 (05): : A530 - A530
  • [4] VERAPAMIL AND DIET HALT PROGRESSION OF ATHEROSCLEROSIS IN CHOLESTEROL-FED RABBITS
    SIEVERS, R
    RASHID, T
    GARRETT, J
    BLUMLEIN, S
    PARMLEY, W
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1986, 7 (02) : A58 - A58
  • [5] Kefiran Reduces Atherosclerosis in Rabbits Fed a High Cholesterol Diet
    Uchida, Masashi
    Ishii, Itsuko
    Inoue, Chika
    Akisato, Yoshie
    Watanabe, Kenta
    Hosoyama, Saori
    Toida, Toshihiko
    Ariyoshi, Noritaka
    Kitada, Mitsukazu
    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 2010, 17 (09) : 980 - 988
  • [6] DEXAMETHASONE SUPPRESSES ATHEROSCLEROSIS IN RABBITS FED A HIGH CHOLESTEROL DIET
    HALLERMAYER, G
    ANTON, H
    BRUCKMAIER, C
    MILOTZKE, W
    SCHIEROK, HJ
    ARTERIOSCLEROSIS, 1990, 10 (05): : A792 - A793
  • [7] EFFECT OF SKIM MILK ON PROGRESSION OF ATHEROSCLEROSIS IN CHOLESTEROL-FED RABBITS
    AGGARWAL, RAK
    KANSAL, VK
    INDIAN JOURNAL OF MEDICAL RESEARCH SECTION B-BIOMEDICAL RESEARCH OTHER THAN INFECTIOUS DISEASES, 1992, 96 : 53 - 59
  • [8] ATHEROSCLEROSIS IN RABBITS FED A LOW CHOLESTEROL DIET FOR 5 YEARS
    WILSON, RB
    MILLER, RA
    MIDDLETON, CC
    KINDEN, D
    ARTERIOSCLEROSIS, 1982, 2 (03): : 228 - 241
  • [9] Spirulina Prevents Atherosclerosis by Reducing Hypercholesterolemia in Rabbits Fed a High-Cholesterol Diet
    Cheong, Sun Hee
    Kim, Mi Yeon
    Sok, Dai-Eun
    Hwang, Seock-Yeon
    Kim, Jin Hee
    Kim, Hye Ran
    Lee, Jeung Hee
    Kim, Yun-Bae
    Kim, Mee Ree
    JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 2010, 56 (01) : 34 - 40
  • [10] Zinc supplementation inhibits lipid peroxidation and atherosclerosis in rabbits fed a high cholesterol diet
    Jenner, AM
    Ren, MQ
    Rajendran, R
    Ning, P
    Huat, BTK
    Watt, F
    Halliwell, B
    FREE RADICAL RESEARCH, 2005, 39 : S63 - S63
12345