Functionalization Reactions of Various Pyrazole-3-carboxylic Acid Chlorides with Some Ureas

被引:2
|
作者
Ilhan, Ilhan Ozer [1 ]
Demirkol, Kazim [1 ]
Onal, Zulbiye [1 ]
Akkoc, Senem [1 ]
Cadir, Mehmet [1 ]
机构
[1] Erciyes Univ, Fac Sci, Dept Chem, TR-38039 Kayseri, Turkey
关键词
Furan-2,3-dione; Pyrazole-3-carboxylic acid; Cyclic oxalyl compounds; Pyrazole-3-carboxylic acid chlorides; CYCLIC OXALYL COMPOUNDS; 4-BENZOYL-1,5-DIPHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID; CYCLIZATION REACTIONS; HETEROCYCLES; DERIVATIVES;
D O I
10.14233/ajchem.2014.16000
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The 1H-pyrazole-3-carboxylic acids 2 or their remarkably stable acid chlorides 3 can easily be converted into the corresponding 1H-pyrazole-3-carbonyl-N'-urea derivatives (5a-k) from reaction with urea nucleophiles. It has been demonstrated that with the variation in reaction conditions, the reaction changes thus leading to different products. All newly synthesized compounds were characterized by elemental analysis, FT-IR, H-1 and C-13 NMR spectral data. All compounds were compared with their previous analogues.
引用
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页码:2365 / 2368
页数:4
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