Damage Control Surgery after Burn Injury: A Narrative Review

被引:6
|
作者
Rennekampff, Hans-Oliver [1 ]
Tenenhaus, Mayer [1 ]
Huss, Fredrik [1 ]
机构
[1] Rhein Maas Klinikum, Dept Plast Surg Hand & Burn Surg, D-52146 Wurselen, Germany
来源
EUROPEAN BURN JOURNAL | 2022年 / 3卷 / 02期
关键词
burn; damage control; debridement; surgery; second hit; CERIUM NITRATE; WOUND EXCISION; LETHAL TRIAD; SURVIVAL; TRANSFUSION; TRAUMA; BLOOD; EXPRESSION; MORTALITY; DAMPS;
D O I
10.3390/ebj3020024
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Burn injuries with cutaneous loss result in a severe systemic response when profound injuries exceed 20% of the total body surface area. The management of severely burned patients is a complex and dynamic process. Timely and safe operative interventions are critical components of multidisciplinary care. Effective management of severely burned patients, their cutaneous injuries, and the associated systemic disease requires a comprehensive understanding of the pathophysiologic response to trauma, objective indicators of patient status, and an appreciation for the dynamic nature of these parameters. Progress in both clinical and basic science research has advanced our understanding of these concepts and our approach to the management of burn patients. Incorporating concepts such as early total care, damage control surgery (DCS), and safe definitive surgery (SDS) in the polytraumatized patient may further aid in optimizing outcomes and quality of care for burn patients. This article connects current knowledge of the lethal triad, inflammation, immunosuppression, and eschar-derived toxins, with surgical burn care, especially burn wound debridement. The concepts of DCS and SDS for the care and management of burn patients are strongly advocated. Experimental and clinical studies are encouraged to validate these concepts in an effort to optimize patient outcomes.
引用
收藏
页码:278 / 289
页数:12
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