Association of Left Coronary Artery Disease with Diabetes and Hypertension among patients presenting with Chest Pain

Background: Coronary artery disease (CAD) is the major cause of death in United States1 as well as globally. It usually present as severe chest pain. Aim: To determine the incidence of left coronary artery disease (LCAD) among high risk patients presenting with chest pain. Methodology: This study was conducted in Department of cardiology, Services hospital, Lahore for 6 months. Both genders (n=246) with age (35-75years) were enrolled in the study. All patients underwent coronary angiography which was a gold standard to diagnose coronary artery disease.: Collected data was analysed using SPSS Version 11.0. Numerical data like age and gender with diabetes and hypertension variables were presented as frequency and percentages.Chi Square test was applied with significant p value (<= 0.05). Results: Patients (n=246) with mean age of 52.42 +/- 9.39 years. Out of 246 patients 160 (65.04%) were males and 86(34.96%) were females. Out of 246 patients, 190(77.20%) patients had left main coronary artery disease. Out of 134 hypertensive patients, 105(78.20%) patients had left main coronary artery disease. Out of 118 diabetic patients, 92(78%) patients had left main coronary artery disease. Left main coronary artery disease was insignificantly associated with diabetes and hypertension as (P>0.05). Conclusion: We concluded that in patients of ACS, diabetes and hypertension are risk factors for LMCA stenosis and predictor of serious complications of coronary heart disease.