Correlation of intellectual impairment in Parkinson's disease with FDG PET scan

被引：12

作者：

Wu, JC ^{[1
]}

Iacono, R

Ayman, M

Salmon, E

Lin, SD

Carlson, J

Keator, D

Lee, A

Najafi, A

Fallon, J

机构：

[1] Loma Linda Univ, Sch Med, Dept Psychiat & Human Behav, Brain Imaging Ctr, Loma Linda, CA 92350 USA

[2] Univ Calif Irvine, Dept Anat, Irvine, CA 92697 USA

来源：

NEUROREPORT | 2000年 / 11卷 / 10期

关键词：

emission computed tomography; FDG; Parkinson's disease;

D O I：

10.1097/00001756-200007140-00016

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This study investigated the relationship between regional glucose metabolism with intellectual impairment in patients with Parkinson's disease using statistical parametric mapping. Regional cerebral glucose metabolism using [F-18]deoxyglucose (FDG) PET scans were performed on 10 patients with Parkinson's disease. We used the intellectual impairment score from the UPDRS. PET scans were analyzed with SPM96. Patients showed significant positive correlations with left limbic structures such as the cingulate gyrus, parahippocampal gyrus, and medial frontal gyrus. Patients showed significant negative correlations with associative neocortical posterior structures such as bilateral parietal and occipital gyrus. There were significant relationships between regional glucose metabolism and intellectual impairment. NeuroReport 11:2139-2144 (C) 2000 Lippincott Williams & Wilkins.

引用

页码：2139 / 2144

页数：6

共 50 条

[1] FDG-PET findings of Parkinson's disease with mild cognitive impairment
Lee, M. -S.
Lyoo, C. H.
Jeong, Y.
Ryu, Y. H.
Rinne, J.
PARKINSONISM & RELATED DISORDERS, 2007, 13 : S156 - S157
[2] Diagnosis of dementia in Parkinson's disease with FDG PET
Liepelt, I.
Reimold, M.
Maetzler, W.
Reischel, G.
Schweitzer, K.
Gaenslen, A.
Godau, J.
Gasser, T.
Machulla, H.-J.
Bares, R.
Berg, D.
MOVEMENT DISORDERS, 2007, 22 : S161 - S161
[3] Visual hallucination in Parkinson's disease with FDG PET
Nagano-Saito, A
Washimi, Y
Arahata, Y
Iwai, K
Kawatsu, S
Ito, K
Nakamura, A
Abe, Y
Yamada, T
Kato, T
Kachi, T
MOVEMENT DISORDERS, 2004, 19 (07) : 801 - 806
[4] Biological Phenotype of Cognitive Impairment in Parkinson's Disease: A 18FDG-PET Study.
Prieto, E.
Garrastachu, P.
Arbizu, J.
Marti-Climent, J. M.
Garcia, D.
Lamet, I.
Clavero, P.
Obeso, J. A.
Richter, J. A.
Rodriguez, M. C.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2008, 35 : S314 - S314
[5] Assessment of Parkinson's disease with dementia by FDG-PET
Higashi, Y.
Kamada, H.
Tabata, M.
MOVEMENT DISORDERS, 2010, 25 (07) : S319 - S319
[6] DEPRESSION, INTELLECTUAL IMPAIRMENT, AND PARKINSON DISEASE
MAYEUX, R
STERN, Y
ROSEN, J
LEVENTHAL, J
NEUROLOGY, 1981, 31 (06) : 645 - 650
[7] Clinical and cerebral FDG PET scan in a patient with Krabbe's disease
Al-Essa, MA
Bakheet, SM
Patay, ZJ
Powe, JE
Ozand, PT
PEDIATRIC NEUROLOGY, 2000, 22 (01) : 44 - 47
[8] Applications of MRI and FDG PET Imaging in Parkinson's Disease Diagnosis
Gujral, Jaskeerat
Gandhi, Om
Subtirelu, Robert
Gerlach, Alexander
Werner, Thomas
Revheim, Mona-Elisabeth
Alavi, Abass
JOURNAL OF NUCLEAR MEDICINE, 2024, 65
[9] Combined FDG PET and event-related potentials study of the cognitive impairment mechanisms in patients with Parkinson's Disease
Khomenko, I.
Kataeva, G.
Pronina, M.
Kropotov, Y.
Irishina, Y.
Susin, D.
Gromova, E.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2018, 45 : S395 - S395
[10] Correlation of Homocysteine Levels with Cognitive Impairment of Parkinson's Disease
Yu, Q. T.
Kong, M.
Ba, M. W.
Yu, L.
Yu, G. P.
Liang, H.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2019, 67 : S604 - S605

← 1 2 3 4 5 →