共 50 条
- [21] Dual HDAC/BRD4 inhibitors against cancerMedicinal Chemistry Research, 2021, 30 : 1822 - 1836Negar Omidkhah论文数: 0 引用数: 0 h-index: 0机构: Mashhad University of Medical Sciences,Biotechnology Research Center, Pharmaceutical Technology InstituteFarzin Hadizadeh论文数: 0 引用数: 0 h-index: 0机构: Mashhad University of Medical Sciences,Biotechnology Research Center, Pharmaceutical Technology InstituteRazieh Ghodsi论文数: 0 引用数: 0 h-index: 0机构: Mashhad University of Medical Sciences,Biotechnology Research Center, Pharmaceutical Technology Institute
- [22] Design and synthesis of dual ALK/BRD4 inhibitorsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255Watts, Ellen论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Div Canc Therapeut, London, England Inst Canc Res, Div Canc Therapeut, London, EnglandTucker, Elizabeth论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Paediat Solid Tumour Biol & Therapeut Team, London, England Inst Canc Res, Div Canc Therapeut, London, England论文数: 引用数: h-index:机构:Bellenie, Benjamin论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Div Canc Therapeut, London, England Inst Canc Res, Div Canc Therapeut, London, EnglandKnapp, Stefan论文数: 0 引用数: 0 h-index: 0机构: Goethe Univ Frankfurt, Frankfurt, Germany Struct Genom Consortium, Oxford, England Inst Canc Res, Div Canc Therapeut, London, EnglandChesler, Louis论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Paediat Solid Tumour Biol & Therapeut Team, London, England Inst Canc Res, Div Canc Therapeut, London, EnglandHoelder, Swen论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Div Canc Therapeut, London, England Inst Canc Res, Div Canc Therapeut, London, England
- [23] Discovery of novel 4-phenylquinazoline-based BRD4 inhibitors for cardiac fibrosisActa Pharmaceutica Sinica B, 2022, 12 (01) : 291 - 307Zhangxu He论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou UniversityHaomiao Jiao论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou UniversityQi An论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou UniversityXin Zhang论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou UniversityDan Zengyangzong论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou UniversityJiale Xu论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou UniversityHongmin Liu论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou UniversityLiying Ma论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University China Meheco Topfond Pharmaceutical Co. State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou UniversityWen Zhao论文数: 0 引用数: 0 h-index: 0机构: State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University
- [24] Discovery of novel 4-phenylquinazoline-based BRD4 inhibitors for cardiac fibrosisACTA PHARMACEUTICA SINICA B, 2022, 12 (01) : 291 - 307He, Zhangxu论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R ChinaJiao, Haomiao论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R ChinaAn, Qi论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R ChinaZhang, Xin论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R ChinaZengyangzong, Dan论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R ChinaXu, Jiale论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R ChinaLiu, Hongmin论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R ChinaMa, Liying论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China China Meheco Topfond Pharmaceut Co, Zhumadian 463000, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R ChinaZhao, Wen论文数: 0 引用数: 0 h-index: 0机构: Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China Zhengzhou Univ, Sch Pharmaceut Sci, Minist Educ China,Key Lab Adv Pharmaceut Technol, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450001, Peoples R China
- [25] BRD4 degradation by PROTACs represents a more effective therapeutic strategy than BRD4 inhibitors in ovarian cancerCANCER RESEARCH, 2016, 76Raina, Kanak论文数: 0 引用数: 0 h-index: 0Lu, Jing论文数: 0 引用数: 0 h-index: 0Qian, Yimin论文数: 0 引用数: 0 h-index: 0Altieri, Martha论文数: 0 引用数: 0 h-index: 0Dong, Hanging论文数: 0 引用数: 0 h-index: 0Wang, Jing论文数: 0 引用数: 0 h-index: 0Chen, Xin论文数: 0 引用数: 0 h-index: 0Crew, Andrew论文数: 0 引用数: 0 h-index: 0Coleman, Kevin论文数: 0 引用数: 0 h-index: 0Crews, Craig论文数: 0 引用数: 0 h-index: 0Winkler, James论文数: 0 引用数: 0 h-index: 0
- [26] Fragment-based approaches to TB drugsPARASITOLOGY, 2018, 145 (02) : 184 - 195Marchetti, Chiara论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandChan, Daniel S. H.论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandCoyne, Anthony G.论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandAbell, Chris论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England
- [27] Fragment-based approaches to enzyme inhibitionCURRENT OPINION IN BIOTECHNOLOGY, 2007, 18 (06) : 489 - 496Ciulli, Alessio论文数: 0 引用数: 0 h-index: 0机构: Univ Chem Lab, Cambridge CB2 1EW, England Univ Chem Lab, Cambridge CB2 1EW, EnglandAbell, Chris论文数: 0 引用数: 0 h-index: 0机构: Univ Chem Lab, Cambridge CB2 1EW, England Univ Chem Lab, Cambridge CB2 1EW, England
- [28] BRD4 is a new therapeutic target in melanomaCANCER RESEARCH, 2013, 73Fontanals-Cirera, Barbara论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, New York, NY USA NYU, Sch Med, New York, NY USASegura, Miguel F.论文数: 0 引用数: 0 h-index: 0机构: Vall Hebron Inst Recerca, Barcelona, Spain NYU, Sch Med, New York, NY USAGaziel-Sovran, Avital论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, New York, NY USA NYU, Sch Med, New York, NY USAGuijarro, Maria V.论文数: 0 引用数: 0 h-index: 0机构: Univ Florida, Gainesville, FL USA NYU, Sch Med, New York, NY USAHanniford, Doug论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, New York, NY USA NYU, Sch Med, New York, NY USAGonzalez-Gomez, Pilar论文数: 0 引用数: 0 h-index: 0机构: Inst Salud Carlos III, Madrid, Spain NYU, Sch Med, New York, NY USAZhang, Weijia论文数: 0 引用数: 0 h-index: 0机构: Mt Sinai Sch Med, New York, NY USA NYU, Sch Med, New York, NY USAZhang, Guantao论文数: 0 引用数: 0 h-index: 0机构: Mt Sinai Sch Med, New York, NY USA NYU, Sch Med, New York, NY USADarvishian, Farbod论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, New York, NY USA NYU, Sch Med, New York, NY USAOhlmeyer, Michael论文数: 0 引用数: 0 h-index: 0机构: Mt Sinai Sch Med, New York, NY USA NYU, Sch Med, New York, NY USAOsman, Iman论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, New York, NY USA NYU, Sch Med, New York, NY USAZhou, Ming-Ming论文数: 0 引用数: 0 h-index: 0机构: Mt Sinai Sch Med, New York, NY USA NYU, Sch Med, New York, NY USAHernando, Eva论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, New York, NY USA NYU, Sch Med, New York, NY USA
- [29] Fragment-based identification of phosphatase inhibitorsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238Rawls, Katherine论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USASoellner, Matthew论文数: 0 引用数: 0 h-index: 0机构: Univ Michigan, Dept Med Chem, Ann Arbor, MI 48109 USA Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USATakeuchi, Jun论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USAImamura, Shinichi论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USABaguley, Tyler论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USAGrundner, Christoph论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USAAlber, Tom论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USAEllman, Jonathan A.论文数: 0 引用数: 0 h-index: 0机构: Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
- [30] Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 InhibitorsJOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (07) : 3272 - 3302Kavanagh, Madeline E.论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandCoyne, Anthony G.论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandMcLean, Kirsty J.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Ctr Synthet Biol Fine & Specialty Chem SYNBIOCHEM, Manchester Inst Biotechnol, Fac Life Sci, 131 Princess St, Manchester M1 7DN, Lancs, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandJames, Guy G.论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandLevy, Colin W.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Ctr Synthet Biol Fine & Specialty Chem SYNBIOCHEM, Manchester Inst Biotechnol, Fac Life Sci, 131 Princess St, Manchester M1 7DN, Lancs, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandMarino, Leonardo B.论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mill Hill Lab, Lab Mycobacterial Metab & Antibiot Res, London NW7 1AA, England Sao Paulo State Univ UNESP, Sch Pharmaceut Sci, BR-4801902 Araraquara, SP, Brazil Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, Englandde Carvalho, Luiz Pedro S.论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mill Hill Lab, Lab Mycobacterial Metab & Antibiot Res, London NW7 1AA, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandChan, Daniel S. H.论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandHudson, Sean A.论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Australian Natl Univ, Res Sch Chem, Coll Phys & Math Sci, Bldg 137,Sullivans Creek Rd, Canberra, ACT 0200, Australia Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandSurade, Sachin论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Biochem, 80 Tennis Court Rd, Cambridge CB2 1GA, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandLeys, David论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Ctr Synthet Biol Fine & Specialty Chem SYNBIOCHEM, Manchester Inst Biotechnol, Fac Life Sci, 131 Princess St, Manchester M1 7DN, Lancs, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandMunro, Andrew W.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Ctr Synthet Biol Fine & Specialty Chem SYNBIOCHEM, Manchester Inst Biotechnol, Fac Life Sci, 131 Princess St, Manchester M1 7DN, Lancs, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, EnglandAbell, Chris论文数: 0 引用数: 0 h-index: 0机构: Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England