Teaching an Old Drug New Tricks

被引：3

作者：

Momcilovic, Milica ^{[1
]}

Shackelford, David B. ^{[1
,2
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Pulm & Crit Care Med, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Jonsson Comprehens Canc Ctr, Los Angeles, CA 90095 USA

来源：

CANCER CELL | 2019年 / 35卷 / 05期

关键词：

METFORMIN; CANCER; INHIBITION;

D O I：

10.1016/j.ccell.2019.04.008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In this issue of Cancer Cell, Elgendy et al. describe the use of intermittent fasting as a strategy to reduce tumor glucose levels and sensitize otherwise resistant tumor cells to metformin. The authors demonstrate that intermittent fasting before metformin treatment sensitized tumors to metformin and significantly reduced tumor growth.

引用

页码：709 / 711

页数：3

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