Perineural Invasion in Cutaneous Squamous Cell Carcinoma

被引:18
|
作者
Perez Garcia, M. P. [1 ]
Mateu Puchades, A. [2 ]
Sanmartin Jimenez, O. [3 ]
机构
[1] Hosp Marina Salud, Serv Dermatol, Alicante, Spain
[2] Hosp Dr Peset, Serv Dermatol, Valencia, Spain
[3] Inst Valenciano Oncol, Serv Dermatol, Valencia, Spain
来源
ACTAS DERMO-SIFILIOGRAFICAS | 2019年 / 110卷 / 06期
关键词
Squamous cell carcinoma; Perineural infiltration; High risk; Radiotherapy; MOHS MICROGRAPHIC SURGERY; SKIN-CANCER; RADIOGRAPHIC FINDINGS; BASAL-CELL; HEAD; SPREAD; NECK; PROGNOSIS; IMPACT; IDENTIFICATION;
D O I
10.1016/j.ad.2018.10.006
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Cutaneous squamous cell carcinoma is sometimes characterized by an increased risk of locoregional recurrence and occasionally distant metastasis. Several clinical and pathological factors, including perineural invasion, have been shown to have prognostic value in this setting. Perineural invasion, that is, the spread of tumor cells into the space surrounding a nerve, is usually an incidental finding. In the presence of symptoms or radiographic evidence of perineural spread, the diagnosis is clinical perineural invasion, which is associated with an increased risk of local recurrence and mortality. (C) 2018 AEDV. Published by Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码:426 / 433
页数:8
相关论文
共 50 条
  • [31] Perineural and lymphovascular invasion in squamous cell carcinoma of the tongue
    Barrett, Andrew W.
    Pratt, Murray K.
    Sassoon, Isabel
    Bisase, Brian S.
    Newman, Laurence
    Tighe, John V.
    Norris, Paul M.
    Dhanda, Jag
    Gulati, Aakshay
    JOURNAL OF ORAL PATHOLOGY & MEDICINE, 2021, 50 (01) : 32 - 38
  • [32] SQUAMOUS-CELL CARCINOMA OF SKIN WITH PERINEURAL INVASION
    LAWRENCE, N
    COTTEL, WI
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1994, 31 (01) : 30 - 33
  • [33] Perineural Invasion of Occult Cutaneous Squamous Cell Carcinoma Mimicking Tolosa-Hunt Syndrome
    Stubbing-Moore, Alex
    Uraiby, Hussein
    Lam, Vincent
    Anwar-Bhatti, Samira
    NEURO-OPHTHALMOLOGY, 2025, 49 (01) : 87 - 94
  • [34] P75NGFR immunostaining for the detection of perineural invasion by cutaneous squamous cell carcinoma
    Kelso, RL
    Colome-Grimmer, MI
    Uchida, T
    Wang, HQ
    Wagner, RF
    DERMATOLOGIC SURGERY, 2006, 32 (02) : 177 - 183
  • [35] Extensive Perineural Invasion vs Nerve Caliber to Assess Cutaneous Squamous Cell Carcinoma Prognosis
    Massey, Paul R.
    Wang, David M.
    Murad, Fadi
    Mulvaney, Patrick
    Moore, Kevin
    Okhovat, Jean-Phillip
    Russell-Goldman, Eleanor
    Lin, William M.
    Piris, Adriano
    Huilgol, Shyamala C.
    Ruiz, Emily S.
    Schmults, Chrysalyne D.
    JAMA DERMATOLOGY, 2023, 159 (12) : 1332 - 1338
  • [36] Management of periocular cutaneous squamous cell carcinoma with perineural invasion: a case series and literature review
    Clark, Thomas J. E.
    Harris, Gerald J.
    ORBIT-THE INTERNATIONAL JOURNAL ON ORBITAL DISORDERS-OCULOPLASTIC AND LACRIMAL SURGERY, 2022, 41 (01): : 34 - 43
  • [37] Cutaneous squamous cell carcinoma with extensive perineural invasion and perineural cyst formation without regional lymph node metastases
    Miyagawa, Fumi
    Hirose, Chiharu
    Fukumoto, Takaya
    Asai, Hideki
    Kobayashi, Nobuhiko
    Asada, Hideo
    JOURNAL OF DERMATOLOGY, 2015, 42 (09): : 930 - 931
  • [38] Surgical resection for clinical perineural invasion from cutaneous squamous cell carcinoma of the head and neck
    Panizza, Benedict
    Solares, C. Arturo
    Redmond, Michael
    Parmar, Priya
    O'Rourke, Peter
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2012, 34 (11): : 1622 - 1627
  • [39] Cutaneous head and neck basal and squamous cell carcinomas with perineural invasion
    Mendenhall, William M.
    Ferlito, Alfio
    Takes, Robert P.
    Bradford, Carol R.
    Corry, June
    Fagan, Johannes J.
    Rinaldo, Alessandra
    Strojan, Primoz
    Rodrigo, Juan P.
    ORAL ONCOLOGY, 2012, 48 (10) : 918 - 922
  • [40] NEURAL CELL ADHESION MOLECULE EXPRESSION: NO CORRELATION WITH PERINEURAL INVASION IN CUTANEOUS SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
    Solares, C. Arturo
    Brown, Ian
    Boyle, Glen M.
    Parsons, Peter G.
    Panizza, Benedict
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2009, 31 (06): : 802 - 806