Gut microbiota and hematopoietic stem cell transplantation: where do we stand?

被引：46
|
作者：
Zama, D. [1 ]
Biagi, E. [2 ]
Masetti, R. [1 ]
Gasperini, P. [1 ]
Prete, A. [1 ]
Candela, M. [2 ]
Brigidi, P. [2 ]
Pession, A. [1 ]
机构：
[1] Univ Bologna, St Orsola Malpighi Hosp, Dept Pediat, Pediat Oncol & Haematol Unit Lalla Seragnoli, Bologna, Italy
[2] Univ Bologna, Dept Pharm & Biotechnol, Bologna, Italy
来源：
BONE MARROW TRANSPLANTATION | 2017年 / 52卷 / 01期
关键词：
VERSUS-HOST-DISEASE; BLOOD-STREAM INFECTION; REGULATORY T-CELLS; CHAIN FATTY-ACIDS; FECAL MICROBIOTA; INTESTINAL MICROBIOTA; METAGENOMIC ANALYSIS; PEDIATRIC-PATIENTS; DENDRITIC CELLS; BACTERIAL;
D O I：
10.1038/bmt.2016.173
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Advances in biological techniques have potentiated great progresses in understanding the interaction between human beings and the similar to 10 to 100 trillion microbes living in their gastrointestinal tract: gut microbiota (GM). In this review, we describe recent emerging data on the role of GM in hematopoietic stern cell transplantation, with a focus on immunomodulatory properties in the immune system recovery and the impact in the development of the main complications, as GvHD and infections.
引用
收藏
页码：7 / 14
页数：8
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