Specific features of lincomycin and gentamicin sorption from aqueous solutions of their salts and bases by monocarboxyl cellulose

Sorption of antibiotics lincomycin and gentamicin from aqueous solutions of their salts and bases by the samples of monocarboxyl cellulose with different content of carboxyl groups was studied. The nature of sorption interactions and factors affecting this process was disclosed. Electrostatic interactions were shown to play a determining role in the mechanism of the antibiotic binding with monocarboxyl cellulose. Single-charged lincomycin was found to be sorbed by monocarboxyl cellulose via stoichiometric binding characterized by the 1 : 1 sorbent-to-sorbate ratio. Multicharged gentamicin was also sorbed from solutions of its sulfate and base due to electrostatic interactions; however, several protonated amino groups of gentamicin molecule are involved in binding, thus resulting in the cross-linking of monocarboxyl cellulose macromolecules.