Synthesis and Antibacterial Activity of Copper(I) Complexes with Bisbenzoylthiourea

被引:2
|
作者
Zhao, Meng-Meng [1 ]
Dong, Xiu-Yan [1 ]
Li, Gang [1 ]
Yang, Xiao-Qin [1 ]
机构
[1] Lanzhou Jiaotong Univ, Sch Chem & Biol Engn, Lanzhou 730070, Peoples R China
关键词
Bisbenzoylthiourea; Complex; Synthesis; Antibacterial activity; CRYSTAL-STRUCTURE; PALLADIUM(II) COMPLEXES; NICKEL(II) COMPLEXES; ANTIFUNGAL ACTIVITY; THIOSEMICARBAZONES; COORDINATION; LIGANDS;
D O I
10.14233/ajchem.2014.15897
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Two copper(I) complexes, [Cu(L)] ClO4 (1) and [Cu(L) Cl]center dot C2H5OH (2), have been synthesized by the reaction of copper(II) perchlorate hexahydrate and copper(II) chloride dihydrate with N, N'-(1,2-dimethylene) bisbenzoylthiourea (L), respectively and characterized by elemental analyses as well as IR spectra and TG-DTA analyses. Antibacterial activity assays exhibit MIC50 values of the two copper(I) complexes comparable to standard drugs for both Gram-positive and Gram-negative bacteria, both of them show stronger antibacterial activity.
引用
收藏
页码:277 / 279
页数:3
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