Photoactivatable CaMKII: Rewiring the Brain, One Synapse at a Time

被引：0
|
作者：
Gee, Christine E. [1 ]
Oertner, Thomas G. [1 ]
机构：
[1] Univ Med Ctr Hamburg Eppendorf, Inst Synapt Physiol, Ctr Mol Neurobiol Hamburg ZMNH, Hamburg, Germany
来源：
TRENDS IN NEUROSCIENCES | 2021年 / 44卷 / 04期
关键词：
D O I：
10.1016/j.tins.2021.02.004
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A recent article by Shibata et al. introduces the engineered photoactiva table enzyme paCaMKII. Activation of this new tool is sufficient to induce long-term potentiation (LTP) of hippocampal synapses in slice culture and in intact animals, thereby expanding the existing toolkit for light-induced modification of brain connectivity at the synaptic level.
引用
收藏
页码：246 / 247
页数：2
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