Diversity of homology-dependent gene silencing strategies in fungi

被引:37
|
作者
Faugeron, G
机构
[1] Univ Paris 07, CNRS, UMR 7592, Inst Jacques Monod, F-75251 Paris 05, France
[2] Univ Paris 06, F-75251 Paris, France
关键词
D O I
10.1016/S1369-5274(00)00066-7
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The experimental introduction of DIVA in fungi has revealed a variety of gene inactivation strategies triggered in response to the presence of homologous nucleic acid sequences. These homology effects reveal distinct classes of gene inactivation resulting from hypermutation or relying on regulatory mechanisms that operate at either the transcriptional or the post-transcriptional level.
引用
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页码:144 / 148
页数:5
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