Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy

被引：47

作者：

Liu, Xuanyu ^{[1
,2
]}

Ma, Yi ^{[1
,2
]}

Yin, Kunlun ^{[1
,2
]}

Li, Wenke ^{[1
,2
]}

Chen, Wen ^{[1
,2
]}

Zhang, Yujing ^{[1
,2
]}

Zhu, Changsheng ^{[2
,3
]}

Li, Tianjiao ^{[1
,2
]}

Han, Bianmei ^{[1
,2
]}

Liu, Xuewen ^{[1
,2
]}

Wang, Shuiyun ^{[2
,3
]}

Zhou, Zhou ^{[1
,2
]}

机构：

[1] Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Beijing Key Lab Mol Diagnost Cardiovasc Dis, Ctr Lab Med,Fuwai Hosp,State Key Lab Cardiovasc D, Beijing 100037, Peoples R China

[2] Peking Union Med Coll, Beijing 100037, Peoples R China

[3] Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, State Key Lab Cardiovasc Dis, Dept Cardiovasc Surg,Fuwai Hosp, Beijing 100037, Peoples R China

来源：

SCIENTIFIC DATA | 2019年 / 6卷 / 1期

基金：

中国国家自然科学基金;

关键词：

TRANSCRIPTOME;

D O I：

10.1038/s41597-019-0094-6

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Hypertrophic cardiomyopathy (HCM) represents one of the most common heritable heart diseases. However, the signalling pathways and regulatory networks underlying the pathogenesis of HCM remain largely unknown. Here, we present a strand-specific RNA-seq dataset for both coding and lncRNA profiling in myocardial tissues from 28 HCM patients and 9 healthy donors. This dataset constitutes a valuable resource for the community to examine the dysregulated coding and lncRNA genes in HCM versus normal conditions.

引用

页数：7

共 50 条

[11] Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA
Kate M Broadbent
Jill C Broadbent
Ulf Ribacke
Dyann Wirth
John L Rinn
Pardis C Sabeti
BMC Genomics, 16
[12] Strand-Specific RNA-Seq Provides Greater Resolution of Transcriptome Profiling
Mills, James Dominic
Kawahara, Yoshihiro
Janitz, Michael
CURRENT GENOMICS, 2013, 14 (03) : 173 - 181
[13] UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq
Sun, Zhifu
Nair, Asha
Chen, Xianfeng
Prodduturi, Naresh
Wang, Junwen
Kocher, Jean-Pierre
SCIENTIFIC REPORTS, 2017, 7
[14] UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq
Zhifu Sun
Asha Nair
Xianfeng Chen
Naresh Prodduturi
Junwen Wang
Jean-Pierre Kocher
Scientific Reports, 7
[15] Preliminary RNA-Seq Analysis of Long Non-Coding RNAs Expressed in Human Term Placenta
Majewska, Marta
Lipka, Aleksandra
Paukszto, Lukasz
Jastrzebski, Jan Pawel
Gowkielewicz, Marek
Jozwik, Marcin
Majewski, Mariusz Krzysztof
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (07)
[16] RNA-Seq Analysis of Mycobacterium avium Non-Coding Transcriptome
Ignatov, Dmitriy
Malakho, Sofia
Majorov, Konstantin
Skvortsov, Timofey
Apt, Alexander
Azhikina, Tatyana
PLOS ONE, 2013, 8 (09):
[17] RNA-seq of psoriasis case-control sample reveals coexpression of coding genes and long non-coding RNA transcripts
Ahn, R.
Gupta, R.
Lai, K.
Dimon, M.
Pons, J.
Liao, W.
EXPERIMENTAL DERMATOLOGY, 2014, 23 : 7 - 7
[18] RNA-seq profiling of mRNA associated with hypertrophic cardiomyopathy
Ren, Chang-Wei
Liu, Jia-Ji
Li, Jin-Hua
Li, Jing-Wei
Dai, Jiang
Lai, Yong-Qiang
MOLECULAR MEDICINE REPORTS, 2016, 14 (06) : 5573 - 5586
[19] Characterization of the Myometrial Transcriptome of Long Non-coding RNA Genes in Human Labor by High-Throughput RNA-seq
Yihong Luo
Long Cui
Lina Chen
Lele Wang
Kaiyuan Ji
Huishu Liu
Reproductive Sciences, 2022, 29 : 2885 - 2893
[20] Characterization of the Myometrial Transcriptome of Long Non-coding RNA Genes in Human Labor by High-Throughput RNA-seq
Luo, Yihong
Cui, Long
Chen, Lina
Wang, Lele
Ji, Kaiyuan
Liu, Huishu
REPRODUCTIVE SCIENCES, 2022, 29 (10) : 2885 - 2893

← 1 2 3 4 5 →