Pharmacophore models for subtype-selective analogs of somatostatin (SRIF) based on NMR structures

被引:0
|
作者
Grace, Christy R. R. [1 ]
Koerber, Steven C. [1 ]
Erchegyi, Judit [1 ]
Durrer, Lukas [1 ]
Reubi, Jean Claude [1 ]
Rivier, Jean [1 ]
Riek, Roland [1 ]
机构
[1] Salk Inst Biol Studies, Struct Biol Lab, La Jolla, CA 92037 USA
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:726 / 727
页数:2
相关论文
共 50 条
  • [21] Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists
    Li, Derun
    Wu, Zhicai
    Yu, Yang
    Ball, Richard G.
    Guo, Liangqin
    Sherer, Edward
    He, Shuwen
    Hong, Qingmei
    Lai, Zhong
    Qi, Hongbo
    Quang Truong
    Yang, David X.
    Chicchi, Gary G.
    Tsao, Kwei-Lan
    Trusca, Dorina
    Trujillo, Maria
    Pachanski, Michele
    Eiermann, George J.
    Howard, Andrew D.
    Zhou, Yun-Ping
    Zhang, Bei B.
    Nargund, Ravi P.
    Hagmann, William K.
    ACS MEDICINAL CHEMISTRY LETTERS, 2014, 5 (06): : 690 - 695
  • [23] Inhibition of human pancreatic islet insulin release by receptor-selective somatostatin analogs directed to somatostatin receptor subtype 5
    Zambre, Y
    Ling, ZD
    Chen, MC
    Hou, X
    Woon, CW
    Culler, M
    Taylor, JE
    Coy, DH
    Van Schravendijk, C
    Schuit, F
    Pipeleers, DG
    Eizirik, DL
    BIOCHEMICAL PHARMACOLOGY, 1999, 57 (10) : 1159 - 1164
  • [24] What Can Crystal Structures of Aminergic Receptors Tell Us about Designing Subtype-Selective Ligands?
    Michino, Mayako
    Beuming, Thijs
    Donthamsetti, Prashant
    Newman, Amy Hauck
    Javitch, Jonathan A.
    Shi, Lei
    PHARMACOLOGICAL REVIEWS, 2015, 67 (01) : 198 - 213
  • [25] Antiseizure Activity of Novel γ-Aminobutyric Acid (A) Receptor Subtype-Selective Benzodiazepine Analogues in Mice and Rat Models
    Rivas, Felix M.
    Stables, James P.
    Murphree, Lauren
    Edwankar, Rahul V.
    Edwankar, Chitra R.
    Huang, Shengming
    Jain, Hiteshkumar D.
    Zhou, Hao
    Majumder, Samarpan
    Sankar, Subramanian
    Roth, Bryan L.
    Ramerstorfer, Joachim
    Furtmueller, Roman
    Sieghart, Werner
    Cook, James A.
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (07) : 1795 - 1798
  • [26] Pharmacological effects of nonselective and subtype-selective nicotinic acetylcholine receptor agonists in animal models of persistent pain
    Gao, Baoxi
    Hierl, Markus
    Clarkin, Kristie
    Juan, Todd
    Nguyen, Hung
    van der Valk, Marissa
    Deng, Hong
    Guo, Wenhong
    Lehto, Sonya G.
    Matson, David
    McDermott, Jeff S.
    Knop, Johannes
    Gaida, Kevin
    Cao, Lei
    Waldon, Dan
    Albrecht, Brian K.
    Boezio, Alessandro A.
    Copeland, Katrina W.
    Harmange, Jean-Christophe
    Springer, Stephanie K.
    Malmberg, Annika B.
    McDonough, Stefan I.
    PAIN, 2010, 149 (01) : 33 - 49
  • [27] Electrophysiology-Based Assays to Detect Subtype-Selective Modulation of Human Nicotinic Acetylcholine Receptors
    Kirsch, Glenn E.
    Fedorov, Nikolai B.
    Kuryshev, Yuri A.
    Liu, Zhiqi
    Armstrong, Lucas C.
    Orr, Michael S.
    ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2016, 14 (06) : 333 - 344
  • [28] Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor 3
    Sharma, K
    Patel, YC
    Srikant, CB
    MOLECULAR ENDOCRINOLOGY, 1996, 10 (12) : 1688 - 1696
  • [29] Novel sst4-selective somatostatin (SRIF) agonists.: 4.: Three-dimensional consensus structure by NMR
    Grace, CRR
    Koerber, SC
    Erchegyi, J
    Reubi, JC
    Rivier, J
    Riek, R
    JOURNAL OF MEDICINAL CHEMISTRY, 2003, 46 (26) : 5606 - 5618