Synthesis of chromeno[2,3-c]pyrrol-9(2H)-ones by domino reactions of amino acids with ynones

被引：3

作者：

Miliutina, Mariia ^{[1
]}

Ivon, Yevhen ^{[1
,2
]}

Slobodyanyuk, Evgeniy Y. ^{[1
,2
]}

Ejaz, Syeda Abida ^{[3
]}

Iqbal, Jamshed ^{[3
]}

Villinger, Alexander ^{[1
]}

Iaroshenko, Viktor O. ^{[1
,4
]}

Langer, Peter ^{[1
,5
]}

机构：

[1] Univ Rostock, Inst Chem, 3a Albert Einstein St, D-18059 Rostock, Germany

[2] Taras Shevchenko Natl Univ Kyiv, 62 Volodymyrska St, UA-01033 Kiev, Ukraine

[3] COMSATS Inst Informat Technol, Ctr Adv Drug Res, Abbottabad 22060, Pakistan

[4] Ctr Mol & Macromol Studies, 112 Sienkiewicza St, PL-90363 Lodz, Poland

[5] Univ Rostock, Leibniz Inst Katalyse eV, 29a Albert Einstein St, D-18059 Rostock, Germany

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2019年 / 55卷 / 4-5期

关键词：

amino acids; chromeno[2; 3-c]pyrrol-9(2H)-ones; heterocycles; alkaline phosphatase inhibitory activity; domino reactions; DISCOVERY;

D O I：

10.1007/s10593-019-02481-x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of novel chromeno[2,3-c]pyrrol-9(2H)-ones via domino reaction of amino acids with aromatic ,-ynones is described. Obtained chromeno[2,3-c]pyrrol-9(2H)-ones possess phosphatase inhibitory activity.

引用

页码：465 / 468

页数：4

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