Exploring ATAD2 Bromodomain Structure And Function Differences In The Dynamic Epigenetic Landscape

被引：0
|
作者：
Malone, Kiera [1 ]
Glass, Karen [2 ]
Nix, Jay [3 ]
机构：
[1] Univ Vermont, Burlington, VT 05405 USA
[2] Albany Coll Pharm & Hlth Sci, Pharmaceut Sci, Albany, NY USA
[3] Mol Biol Consortium, Chicago, IL USA
来源：
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES | 2022年 / 78卷
关键词：
D O I：
10.1107/S2053273322099648
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：A35 / A35
页数：1
相关论文
共 50 条
  • [31] Molecular docking and QSAR analysis of naphthyridone derivatives as ATAD2 bromodomain inhibitors: application of CoMFA, LS-SVM, and RBF neural network
    Sepehri, Bakhtyar
    Rasouli, Zolaikha
    Hassanzadeh, Zeinabe
    Ghavami, Raouf
    MEDICINAL CHEMISTRY RESEARCH, 2016, 25 (12) : 2895 - 2905
  • [32] The bromodomain-containing protein ATAD2 promotes GR-mediated enzalutamide resistance in castration-resistant prostate cancer.
    De La Rosa, Richard
    CANCER RESEARCH, 2021, 81 (13)
  • [33] Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
    Fernandez-Montalvan, Amaury E.
    Berger, Markus
    Kuropka, Benno
    Koo, Seong Joo
    Badock, Volker
    Weiske, Joerg
    Puetter, Vera
    Holton, Simon J.
    Stoekigt, Detlef
    ter Laak, Antonius
    Centrella, Paolo A.
    Clark, Matthew A.
    Dumelin, Christoph E.
    Sigel, Eric A.
    Soutter, Holly H.
    Troast, Dawn M.
    Zhang, Ying
    Cuozzo, John W.
    Keefe, Anthony D.
    Roche, Didier
    Rodeschini, Vincent
    Chaikuad, Apirat
    Diaz-Saez, Laura
    Bennett, James M.
    Fedorov, Oleg
    Huber, Kilian V. M.
    Huebner, Jan
    Weinmann, Hilmar
    Hartung, Ingo V.
    Gorjanacz, Matyas
    ACS CHEMICAL BIOLOGY, 2017, 12 (11) : 2730 - 2736
  • [34] A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification
    Bamborough, Paul
    Chung, Chun-wa
    Demont, Emmanuel H.
    Bridges, Angela M.
    Craggs, Peter D.
    Dixon, David P.
    Francis, Peter
    Furze, Rebecca C.
    Grandi, Paola
    Jones, Emma J.
    Karamshi, Bhumika
    Locke, Kelly
    Lucas, Simon C. C.
    Michon, Anne-Marie
    Mitchell, Darren J.
    Pogany, Peter
    Prinjha, Rab K.
    Rau, Christina
    Maria Roa, Ana
    Roberts, Andrew D.
    Sheppard, Robert J.
    Watson, Robert J.
    JOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (16) : 7506 - 7525
  • [35] The ATAD2 bromodomain binds different acetylation marks on the histone H4 in similar fuzzy complexes (vol 292, pg 16734, 2017)
    Langini, Cassiano
    Caflisch, Amedeo
    Vitalis, Andreas
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 292 (46) : 19121 - 19121
  • [36] Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication
    Cho, Carol
    Ganser, Christian
    Uchihashi, Takayuki
    Kato, Koichi
    Song, Ji-Joon
    COMMUNICATIONS BIOLOGY, 2023, 6 (01)
  • [37] Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication
    Carol Cho
    Christian Ganser
    Takayuki Uchihashi
    Koichi Kato
    Ji-Joon Song
    Communications Biology, 6
  • [38] Exploring the structure and function of temporal networks with dynamic graphlets
    Hulovatyy, Y.
    Chen, H.
    Milenkovic, T.
    BIOINFORMATICS, 2015, 31 (12) : 171 - 180
  • [39] EXPLORING THE EFFECTS OF INDIVIDUAL DIFFERENCES IN FUNCTION STRUCTURE MODELING BEHAVIORS
    Patel, Apurva
    Summers, Joshua D.
    PROCEEDINGS OF ASME 2021 INTERNATIONAL DESIGN ENGINEERING TECHNICAL CONFERENCES AND COMPUTERS AND INFORMATION IN ENGINEERING CONFERENCE, IDETC-CIE2021, VOL 6, 2021,
  • [40] When function follows form: Nuclear compartment structure and the epigenetic landscape of the aging neuron
    Schlachetzki, Johannes C. M.
    Toda, Tomohisa
    Mertens, Jerome
    EXPERIMENTAL GERONTOLOGY, 2020, 133
12345