An analytical method for the determination of perfluorinated compounds in whole blood using acetonitrile and solid phase extraction methods

被引：59
|
作者：
Yeung, Leo W. Y. [1 ,2 ]
Taniyasu, Sachi [1 ]
Kannan, Kurunthachalam [3 ,4 ]
Xu, Della Z. Y. [2 ]
Guruge, Keerthi S. [5 ]
Lam, Paul K. S. [2 ]
Yamashita, Nobuyoshi [1 ]
机构：
[1] Natl Inst Adv Ind Sci & Technol, Tsukuba, Ibaraki 3058569, Japan
[2] City Univ Hong Kong, Dept Biol & Chem, Kowloon, Hong Kong, Peoples R China
[3] SUNY Albany, Wadsworth Ctr, New York State Dept Hlth, Albany, NY 12201 USA
[4] SUNY Albany, Dept Environm Hlth Sci, Albany, NY 12201 USA
[5] Natl Inst Anim Hlth, Safety Res Team, Tsukuba, Ibaraki 3050856, Japan
来源：
JOURNAL OF CHROMATOGRAPHY A | 2009年 / 1216卷 / 25期
关键词：
Whole blood; Acetonitrile; Solid phase extraction; Formic acid; Taurodeoxycholic acid; Perfluorooctanesulfonate; TANDEM MASS-SPECTROMETRY; PERFLUOROOCTANE SULFONATE; ORGANIC FLUORINE; SOUTH CHINA; HUMAN SERUM; SHORT-CHAIN; ACIDS; FLUOROCHEMICALS; MATRICES; SAMPLES;
D O I：
10.1016/j.chroma.2009.04.070
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A method for the analysis of perfluorinated compounds (perfluoroalkyl sulfonates: C4, C6, C8, C10; perfluoroalkyl sulfinates: C6, C8, C10; perfluorooctanesulfonamide, N-ethyl perfluorooctanesulfonamide, N-ethyl perfluorooctanesulfonamidoacetate, perfluorocarboxylates: C4-C14; fluorotelomer carboxylate (7:3, 8:2) in whole blood using acetonitrile and OASIS WAX (R) solid phase extraction (SPE) cartridge was developed. Separation of target compounds in two HPLC columns (ion exchange JJ50-2D and C18 Betasil columns) was examined. Matrix recoveries of the developed methods ranged from 70% to 120%. Separation of possible inferences Such as taurodeoxycholic acid (TDC) was accomplished using an ion exchange JJ50-2D column, and this separation was validated using whole blood of different animals. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：4950 / 4956
页数：7
相关论文
共 50 条
  • [21] Solid phase extraction gas chromatography/electron capture detector method for the determination of organochlorine pesticides in wildlife whole blood.
    Volz, SA
    Johnston, JJ
    Griffin, DL
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 220 : U49 - U49
  • [22] Potential of a simple solid-phase extraction method coupled to analytical and bioanalytical methods for an improved determination of microcystins in algal samples
    Chen, Yi-Min
    Lee, Tzong-Huei
    Lee, Shyh-Jye
    Lin, Jian-Zhi
    Huang, Rang
    Chou, Hong-Nong
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2006, 844 (01): : 134 - 141
  • [23] Solid-phase extraction method for determination of volatile compounds in traditional balsamic vinegar
    Duran Guerrero, Enrique
    Chinnici, Fabio
    Natali, Nadia
    Natera Marin, Ramon
    Riponi, Claudio
    JOURNAL OF SEPARATION SCIENCE, 2008, 31 (16-17) : 3030 - 3036
  • [24] Comparison of the solid phase and liquid-liquid extraction methods for methadone determination in human serum and whole blood samples using gas chromatography/mass spectrometry
    Bratincevic, Maja Versic
    Viskovic, Tanja
    Sutlovic, Davorka
    ARHIV ZA HIGIJENU RADA I TOKSIKOLOGIJU-ARCHIVES OF INDUSTRIAL HYGIENE AND TOXICOLOGY, 2017, 68 (04): : 308 - 314
  • [25] Determination of persistent organochlorine compounds in blood by solid phase micro extraction and GC-ECD
    Lars Röhrig
    Michael Püttmann
    H.-U. Meisch
    Fresenius' Journal of Analytical Chemistry, 1998, 361 : 192 - 196
  • [26] Determination of persistent organochlorine compounds in blood by solid phase micro extraction and GC-ECD
    Rohrig, L
    Puttmann, M
    Meisch, HU
    FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 1998, 361 (02): : 192 - 196
  • [27] Determination of pyronaridine in whole blood by automated solid phase extraction and high-performance liquid chromatography
    Blessborn, D
    Lindegårdh, N
    Ericsson, Ö
    Hellgren, U
    Bergqvist, Y
    THERAPEUTIC DRUG MONITORING, 2003, 25 (03) : 264 - 270
  • [28] MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW
    Tekkeli, Serife Evrim Kepekci
    Durmus, Zehra
    JOURNAL OF THE CHILEAN CHEMICAL SOCIETY, 2019, 64 (02): : 4448 - 4458
  • [29] Determination of beer aroma compounds using headspace solid-phase microcolumn extraction
    Hrivnak, Jan
    Smogrovicova, Daniela
    Nadasky, Pavol
    Lakatosova, Jana
    TALANTA, 2010, 83 (01) : 294 - 296
  • [30] Automated solid-phase extraction method for the determination of atovaquone in plasma and whole blood by rapid high-performance liquid chromatography
    Lindegårdh, N
    Bergqvist, Y
    JOURNAL OF CHROMATOGRAPHY B, 2000, 744 (01): : 9 - 17
12345