Ruthenium-Catalyzed Site-selective Enone Carbonyl Directed ortho-C-H Activation of Aromatics and Heteroaromatics with Alkenes

被引：21
|
作者：
Bakthadoss, Manickam [1 ]
Kumar, Polu Vijay [1 ]
机构：
[1] Pondicherry Univ, Dept Chem, Pondicherry 605014, India
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 14期
关键词：
ortho-olefinated chalcone; C-H activation; BOND ACTIVATION; HYDROGEN BONDS; OLEFINATION; ARENES; FUNCTIONALIZATION; DERIVATIVES; ALKENYLATION; HETEROCYCLE; COMPLEXES; SCAFFOLDS;
D O I：
10.1002/adsc.201800376
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An efficient and versatile protocol for enone carbonyl directed ortho C-H activation of aromatics and heteroaromatics with alkenes for the construction of functionalized ortho-olefinated chalcone derivatives in excellent yields in a regio- and stereoselective fashion has been developed for the first time. This general protocol involves chelation assisted oxidative coupling in the presence of ruthenium catalyst through C-H bond activation. This protocol has been further emphasized by the exhibition of functional group tolerance.
引用
收藏
页码：2650 / 2658
页数：9
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