Intramolecular cyclization of acyl radicals onto the azido group: A new radical approach to cyclized lactams

被引：58

作者：

Benati, L ^{[1
]}

Leardini, R ^{[1
]}

Minozzi, M ^{[1
]}

Nanni, D ^{[1
]}

Spagnolo, P ^{[1
]}

Strazzari, S ^{[1
]}

Zanardi, G ^{[1
]}

机构：

[1] Univ Bologna, Dipartimento Chim Organ A Mangini, I-40136 Bologna, Italy

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 18期

关键词：

D O I：

10.1021/ol026366t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

([)GRAPHICS] Aryl- and alkyl-derived azidoacyl radicals, generated from thiolesters by intramolecular homolytic substitution at the sulfur, can undergo five-and six-membered cyclization onto the azido moiety to give cyclized lactams.

引用

页码：3079 / 3081

页数：3

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