Gold Nanoparticles for Nucleic Acid Delivery

被引：385
|
作者：
Ding, Ya [1 ,2 ]
Jiang, Ziwen [1 ]
Saha, Krishnendu [1 ]
Kim, Chang Soo [1 ]
Kim, Sung Tae [1 ]
Landis, Ryan F. [1 ]
Rotello, Vincent M. [1 ]
机构：
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
[2] China Pharmaceut Univ, Minist Educ, Key Lab Drug Qual Control & Pharmacovigilance, Dept Pharmaceut Anal, Nanjing, Jiangsu, Peoples R China
来源：
MOLECULAR THERAPY | 2014年 / 22卷 / 06期
基金：
美国国家卫生研究院;
关键词：
TRANSDERMAL DRUG-DELIVERY; GENE DELIVERY; SIRNA DELIVERY; MULTIFUNCTIONAL NANOPARTICLES; MAMMALIAN-CELLS; CELLULAR UPTAKE; PLASMID DNA; INORGANIC NANOPARTICLES; SURFACE FUNCTIONALITY; CARBON NANOTUBES;
D O I：
10.1038/mt.2014.30
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Gold nanoparticles provide an attractive and applicable scaffold for delivery of nucleic acids. In this review, we focus on the use of covalent and noncovalent gold nanoparticle conjugates for applications in gene delivery and RNA-interference technologies. We also discuss challenges in nucleic acid delivery, including endosomal entrapment/escape and active delivery/presentation of nucleic acids in the cell.
引用
收藏
页码：1075 / 1083
页数：9
相关论文
共 50 条
  • [41] Diagnosing Antibiotic Resistance Using Nucleic Acid Enzymes and Gold Nanoparticles
    Mohamed, Mohamed A. Abdou
    Kozlowski, Hannah N.
    Kim, Jisung
    Zagorovsky, Kyryl
    Kantor, Melinda
    Feld, Jordan J.
    Mubareka, Samira
    Mazzulli, Tony
    Chan, Warren C. W.
    ACS NANO, 2021, 15 (06) : 9379 - 9390
  • [42] Effect of DNA density immobilized on gold nanoparticles on nucleic acid detection
    Hirao, Gen
    Fukuzumi, Nanami
    Ogawa, Atsushi
    Asahi, Tsuyoshi
    Maeda, Mizuo
    Zako, Tamotsu
    RSC ADVANCES, 2023, 13 (46) : 32398 - 32398
  • [43] Colorimetric Nucleic Acid Detection Based on Gold Nanoparticles with Branched DNA
    Zhang, Zhikun
    Ye, Xiaojie
    Liu, Qingqing
    Hu, Cuixia
    Yun, Jimmy
    Liu, Runjing
    Liu, Yumin
    NANO, 2020, 15 (08)
  • [44] Nucleic Acid Delivery
    Zheng-Rong Lu
    Galen H. Shi
    Pharmaceutical Research, 2023, 40 (1) : 1 - 2
  • [45] The 60-year evolution of lipid nanoparticles for nucleic acid delivery
    Cullis, P. R.
    Felgner, P. L.
    NATURE REVIEWS DRUG DISCOVERY, 2024, 23 (09) : 709 - 722
  • [46] Surface engineering of lipid nanoparticles: targeted nucleic acid delivery and beyond
    Yi Lin
    Qiang Cheng
    Tuo Wei
    Biophysics Reports, 2023, 9 (05) : 255 - 278
  • [47] 2011 Rita Schaffer Lecture: Nanoparticles for Intracellular Nucleic Acid Delivery
    Jordan J. Green
    Annals of Biomedical Engineering, 2012, 40 : 1408 - 1418
  • [48] Silica nanoparticles as a delivery system for nucleic acid-based reagents
    Hom, Christopher
    Lu, Jie
    Tamanoi, Fuyuhiko
    JOURNAL OF MATERIALS CHEMISTRY, 2009, 19 (35) : 6308 - 6316
  • [49] Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery
    Molle, Lara M.
    Smyth, Cameron H.
    Yuen, Daniel
    Johnston, Angus P. R.
    WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2022, 14 (06)
  • [50] LIPIDOID IRON OXIDE NANOPARTICLES ARE A PLATFORM FOR NUCLEIC ACID DELIVERY TO THE LIVER
    Uvarova, V., I
    Nizamov, T. R.
    Abakumov, M. A.
    Vodopyanov, S. S.
    Abakumova, T. O.
    Saltykova, I., V
    Mogilnikov, P. S.
    Shchetinin, I., V
    Majouga, A. G.
    BULLETIN OF RUSSIAN STATE MEDICAL UNIVERSITY, 2018, (06): : 43 - 52
12345