The American Public Is Ready to Accept Human-Animal Chimera Research

被引：16

作者：

Crane, Andrew T. ^{[1
]}

Shen, Francis X. ^{[2
,3
,4
]}

Brown, Jennifer L. ^{[2
,3
]}

Cormack, Warren ^{[2
]}

Ruiz-Estevez, Mercedes ^{[8
]}

Voth, Joseph P. ^{[1
]}

Sawai, Tsutomu ^{[5
,6
]}

Hatta, Taichi ^{[6
]}

Fujita, Misao ^{[5
,6
]}

Low, Walter C. ^{[1
,3
,7
]}

机构：

[1] Univ Minnesota, Dept Neurosurg, Minneapolis, MN 55455 USA

[2] Univ Minnesota, Sch Law, Minneapolis, MN 55455 USA

[3] Univ Minnesota, Grad Program Neurosci, Minneapolis, MN 55455 USA

[4] Massachusetts Gen Hosp, Ctr Law Brain & Behav, Boston, MA 02114 USA

[5] KUIAS Kyoto Univ, Inst Adv Study Human Biol WPI ASHBi, Kyoto, Japan

[6] Kyoto Univ, Ctr iPS Cell Res & Applicat, Uehiro Res Div iPS Cell Eth, Kyoto, Japan

[7] Univ Minnesota, Stem Cell Inst, Minneapolis, MN USA

[8] Recombinetics Inc, Eagan, MN USA

来源：

STEM CELL REPORTS | 2020年 / 15卷 / 04期

关键词：

AMAZONS MECHANICAL TURK; JAPAN;

D O I：

10.1016/j.stemcr.2020.08.018

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

We report findings from a new survey of US public attitudes toward human-animal chimeric embryo (HACE) research, designed to compare with recently reported Japanese survey data. We find that 59% of the US public can personally accept the process of injecting human induced pluripotent stem cells into genetically modified swine embryos and having human tissues produced in a pig's body transplanted into a human. This is greater acceptance than in Japan, and there is even strong acceptance among those with strong religious affiliations and who self-identify as conservatives. We argue that strong public support for HACE research, as well as the emerging literature suggesting that humanization of research animals is very unlikely, should compel the NIH to lift its current moratorium on HACE research.

引用

页码：804 / 810

页数：7

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