Alteration of AAV Capsid Lumenal Residues to Expand Vector Genome Packaging Capacity

被引:0
|
作者
Tiffany, Matthew
Pekrun, Katja
Zhang, Feijie
Kay, Mark A.
机构
[1] Stanford Univ, Dept Pediat, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Genet, Stanford, CA 94305 USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
408
引用
收藏
页码:191 / 191
页数:1
相关论文
共 14 条
  • [1] Alteration of AAV Capsid Lumenal Residues Expands Genome Packaging Capacity
    Tiffany, Matthew R.
    Pekrun, Katja
    Zhang, Feijie
    Kay, Mark A.
    MOLECULAR THERAPY, 2017, 25 (05) : 47 - 47
  • [2] Expanded Packaging Capacity of AAV by Lumenal Charge Alteration
    Tiffany, Matthew
    Kay, Mark A.
    MOLECULAR THERAPY, 2016, 24 : S99 - S100
  • [3] Effect of Genome Size on AAV Vector Packaging
    Wu, Zhijian
    Yang, Hongyan
    Colosi, Peter
    MOLECULAR THERAPY, 2010, 18 (01) : 80 - 86
  • [4] Cross-packaging a vector genome containing densovirus ITR into AAV capsid serotype 2 or 8: possible or not?
    Laugel, M.
    Roblin, A.
    Audrain, C.
    Cheve, C.
    Menard, L.
    Blouin, V.
    Mevel, M.
    Adjali, O.
    Penaud-Budloo, M.
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A49 - A50
  • [5] Vector Genome Length and Self-Complementarity Affect AAV Capsid Uncoating
    Horowitz, Eric D.
    Asokan, Aravind
    MOLECULAR THERAPY, 2012, 20 : S202 - S202
  • [6] Capacity of Viral Genome Packaging and Internal Volumes of AAV Viral Particles
    Adachi, Kei
    Klocke, Kai
    Roy, Preeyam
    Rodricks, Daniel
    Chapman, Michael S.
    Nakai, Hiroyuki
    MOLECULAR THERAPY, 2015, 23 : S17 - S17
  • [7] Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints
    Vandenberghe, L. H.
    Breous, E.
    Nam, H-J
    Gao, G.
    Xiao, R.
    Sandhu, A.
    Johnston, J.
    Debyser, Z.
    Agbandje-McKenna, M.
    Wilson, J. M.
    GENE THERAPY, 2009, 16 (12) : 1416 - 1428
  • [8] Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints
    L H Vandenberghe
    E Breous
    H-J Nam
    G Gao
    R Xiao
    A Sandhu
    J Johnston
    Z Debyser
    M Agbandje-McKenna
    J M Wilson
    Gene Therapy, 2009, 16 : 1416 - 1428
  • [9] Generating Novel AAV Capsid Mutants for Large Genome Packaging Through Protein Libraries and Directed Evolution
    Turunen, Heikki T.
    Vandenberghe, Luk H.
    MOLECULAR THERAPY, 2014, 22 : S118 - S118
  • [10] Improving AAV packaging capacity by enhanced protein trans-splicing at low dual vector doses
    Ferreira, M. V.
    Fernandes, S.
    Almeida, A. I.
    Neto, S.
    Mendes, J. P.
    Silva, R. J. S.
    Peixoto, C.
    Coroadinha, A. S.
    HUMAN GENE THERAPY, 2024, 35 (3-4) : A59 - A59