Disruptions in dopamine transmission within the basal ganglia (BG) produce deficits in voluntary actions, that is, in the interface between cortically-generated goal representation and BG-mediated response selection. Under conditions of dopamine loss in humans and other annuals, responses are impaired when they require internal generation, but are relatively intact when elicited by external stimuli.
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Univ Penn Hlth Syst, Dept Neurol, Parkinsons Dis & Movement Disorders Ctr, Philadelphia, PA USAUniv Penn Hlth Syst, Dept Neurol, Parkinsons Dis & Movement Disorders Ctr, Philadelphia, PA USA
Cantor, CR
Stern, MB
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Univ Penn Hlth Syst, Dept Neurol, Parkinsons Dis & Movement Disorders Ctr, Philadelphia, PA USAUniv Penn Hlth Syst, Dept Neurol, Parkinsons Dis & Movement Disorders Ctr, Philadelphia, PA USA
机构:
Uniwersytet Med Lodzi, Oddzial Klin Chorob Ukladu Pozopiramidowego, WSS Im M sklodowskiej Curie, PL-95100 Zgierz, PolandUniwersytet Med Lodzi, Oddzial Klin Chorob Ukladu Pozopiramidowego, WSS Im M sklodowskiej Curie, PL-95100 Zgierz, Poland
Bogucki, Andrzej
Gaios, Agata
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Uniwersytet Med Lodzi, Oddzial Klin Chorob Ukladu Pozopiramidowego, WSS Im M sklodowskiej Curie, PL-95100 Zgierz, PolandUniwersytet Med Lodzi, Oddzial Klin Chorob Ukladu Pozopiramidowego, WSS Im M sklodowskiej Curie, PL-95100 Zgierz, Poland
机构:
Hop Louis Pasteur, Serv Neurol, Unite Pathol Mouvement, F-06002 Nice 1, FranceHop Louis Pasteur, Serv Neurol, Unite Pathol Mouvement, F-06002 Nice 1, France
Borg, M.
Bayreuther, C.
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Hop Louis Pasteur, Serv Neurol, Unite Pathol Mouvement, F-06002 Nice 1, FranceHop Louis Pasteur, Serv Neurol, Unite Pathol Mouvement, F-06002 Nice 1, France