A case report: acute pancreatitis associated with tacrolimus in kidney transplantation

被引：5
|
作者：
Xu, Junnan [1 ,2 ,3 ]
Xu, Liang [1 ,2 ,3 ]
Wei, Xing [1 ,2 ]
Li, Xiang [1 ,2 ]
Cai, Ming [1 ,2 ,3 ]
机构：
[1] 309th Hosp Peoples Liberat Army, Organ Transplant Inst Peoples Liberat Army, Beijing, Peoples R China
[2] Beijing Key Lab Immunol Regulatory & Organ Transp, Beijing, Peoples R China
[3] Chinese Peoples Liberat Army Gen Hosp, Med Sch Chinese PLA, Beijing, Peoples R China
来源：
BMC NEPHROLOGY | 2019年 / 20卷 / 1期
基金：
中国国家自然科学基金;
关键词：
Acute pancreatitis; Tacrolimus; FK506; Kidney transplantation;
D O I：
10.1186/s12882-019-1395-x
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
BackgroundTacrolimus has been widely used for immunosuppressive therapy in solid organ transplantation (SOT) and allo-geneic stem cell transplantation (allo-SCT) over the past 2 decades. Pancreatitis caused by tacrolimus was rarely reported in kidney transplantation previously.Case presentationHere we presented a case of a 45-year-old male who underwent kidney transplantation and received immunosuppressive therapy of tacrolimus, on day +67 after transplantation he developed acute pancreatitis with extremely high blood concentration of tacrolimus. We excluded other possible causes and speculated tacrolimus was the probable inducer of pancreatitis. After tacrolimus was discontinued and alternated with cyclosporine, he gradually recovered and was discharged home with no relapse.ConclusionTacrolimus can be a probable cause of pancreatitis after kidney transplantation. We recommended clinicians to be aware of the possibility of tacrolimus-induced pancreatitis during tacrolimus treatment.
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Abiraterone Acetate-Associated Acute Pancreatitis: A Case Report
    Buyuksimsek, Mahmut
    Ogul, Ali
    Yetisir, Abdullah Evren
    Koseci, Tolga
    Sumbul, Hilmi Erdem
    AMERICAN JOURNAL OF THERAPEUTICS, 2023, 30 (03) : E296 - E298
  • [42] Acute pancreatitis associated with the antibiotic levofloxacin: A rare case report
    Inban, Pugazhendi
    Gulla, Virali
    Devani, Aarfa
    Akuma, Chinaza Mercy
    Gowthavaram, Chengala Ananyaa
    Hussain, Akbar
    Aung, Lynn Lat Lat
    Jadav, Neel
    Savaliya, Bansi
    Sajjad, Taha
    Khan, Aadil Mahmood
    Akuma, Ogbonnaya
    Kelechi, Anasonye Emmanuel
    CLINICAL CASE REPORTS, 2023, 11 (12):
  • [43] Acute Necrotising Pancreatitis Associated with Leptospirosis-A Case Report
    Jain, Amit Kumar C.
    Mohan, L. N.
    INDIAN JOURNAL OF SURGERY, 2013, 75 (03) : 245 - 246
  • [44] Pancreatic Arteriovenous Malformation Associated With Acute Pancreatitis: A Case Report
    Kawamura, Masahiro
    Hirashita, Teijiro
    Fujinaga, Atsuro
    Tada, Kazuhiro
    Endo, Yuichi
    Ohta, Masayuki
    Inomata, Masafumi
    PANCREAS, 2022, 51 (06) : 710 - 710
  • [45] ACUTE HEMORRHAGIC PANCREATITIS ASSOCIATED WITH ADMINISTRATION OF CHLORTHALIDONE - REPORT OF A CASE
    JONES, MF
    CALDWELL, JR
    NEW ENGLAND JOURNAL OF MEDICINE, 1962, 267 (20): : 1029 - &
  • [46] Painless acute pancreatitis associated with sorafenib treatment: a case report
    Yasuyuki Kobayashi
    Toshiyuki Kanemitu
    Akihito Kamoto
    Mototaka Satoh
    Naoki Mori
    Kenichiro Sekii
    Toshiaki Yoshioka
    Hiroaki Itatani
    Takashi Fujimoto
    Medical Oncology, 2011, 28 : 463 - 465
  • [47] Fatal pancreatic panniculitis associated with acute pancreatitis: A case report
    Lee, Woo Sun
    Kim, Mi Yeon
    Kim, Sang Woo
    Paik, Chang Nyol
    Kim, Hyung Ok
    Park, Young Min
    JOURNAL OF KOREAN MEDICAL SCIENCE, 2007, 22 (05) : 914 - 917
  • [48] Acute pancreatitis associated with mesalamine: A case report and review of the literature
    Manfredini, R
    Bariani, L
    Chierici, F
    Tassi, A
    Rizzioli, E
    Notarstefano, P
    Risichella, IS
    LaCecilia, O
    Mirizio, AM
    Franceschini, F
    Fersini, C
    Gallerani, M
    ADVANCES IN THERAPY, 1996, 13 (04) : 216 - 219
  • [49] Peer review report 1 on "Emergency surgical treatment of complicated acute pancreatitis after kidney transplantation with acute rejection: Case report and literature review"
    不详
    ANNALS OF MEDICINE AND SURGERY, 2016, 5 : S153 - S153
  • [50] Acute Q Fever after Kidney Transplantation: A Case Report
    Xie, Junjie
    Li, Gang
    Lin, Fenwang
    Bai, Zhijie
    Yu, Lixin
    Zhang, Dongjing
    Zhang, Bolun
    Ye, Junsheng
    Yu, Ruohan
    Ye, Junsheng
    Yu, Ruohan
    BRITISH JOURNAL OF HOSPITAL MEDICINE, 2025, 86 (01)
12345