Validation of Alternative Ocular Irritation and Reversibility Assay in Excised Porcine Corneas

被引：0
|
作者：
Piehl, M. [1 ]
Carathers, M. [1 ]
Soda, R. [1 ]
Donovan, A. [1 ]
Cerven, D. [1 ]
机构：
[1] MB Res Labs, Spinnerstown, PA USA
来源：
INTERNATIONAL JOURNAL OF TOXICOLOGY | 2009年 / 28卷 / 01期
关键词：
Ocular irritancy; Alternative toxicology; Ocular reversibility;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P26
引用
收藏
页码：53 / 53
页数：1
相关论文
共 50 条
  • [21] EVALUATION OF TETRAHYMENA-THERMOPHILA AS AN INVITRO ALTERNATIVE TO OCULAR IRRITATION STUDIES IN RABBITS
    SILVERMAN, J
    PENNISI, S
    JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY, 1987, 6 (01): : 33 - 42
  • [22] Update on the validation and regulatory acceptance of alternative tests for skin corrosion and irritation
    Fentem, JH
    Botham, PA
    ATLA-ALTERNATIVES TO LABORATORY ANIMALS, 2004, 32 : 683 - 688
  • [23] Comparison of alternative toxicity test methods for ocular irritation using avian chorioallantoic membrane
    Gilloti, A.
    DeGeorge, G.
    Cerven, D.
    IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2005, 41 : 61A - 61A
  • [24] Assessment of the Cytosensor microphysiometer assay in the COLIPA in vitro eye irritation validation study
    Harbell, JW
    Osborne, R
    Carr, GJ
    Peterson, A
    TOXICOLOGY IN VITRO, 1999, 13 (02) : 313 - 323
  • [25] Two validation programmes for alternative methods to the rabbit eye irritation test in Japan
    Kato, S
    PROGRESS IN THE REDUCTION, REFINEMENT AND REPLACEMENT OF ANIMAL EXPERIMENTATION, 2000, 31 : 571 - 585
  • [26] CORRELATION AND VALIDATION OF ALTERNATIVE METHODS TO THE DRAIZE EYE IRRITATION TEST (OPAL PROJECT)
    BLEIN, O
    ADOLPHE, M
    LAKHDAR, B
    CAMBAR, J
    GUBANSKI, G
    CASTELLI, D
    CONTIE, C
    HUBERT, F
    LATRILLE, F
    MASSON, P
    CLOUZEAU, J
    LEBIGOT, JF
    DESILVA, O
    DOSSOU, KG
    TOXICOLOGY IN VITRO, 1991, 5 (5-6) : 555 - 557
  • [27] Metabolic responses of rabbit corneas to normoxic and hypoxic conditions in the Ex Vivo Eye Irritation Test: An alternative to animal experimentation
    Isabel, Gallego Beatriz
    Markus, Glaudo
    Marc, Urbach
    Norbert, Schrage
    EXPERIMENTAL EYE RESEARCH, 2025, 253
  • [28] THE POLLEN-TUBE GROWTH TEST - A NEW ALTERNATIVE TO THE DRAIZE EYE IRRITATION ASSAY
    KRISTEN, U
    HOPPE, U
    PAPE, W
    JOURNAL OF THE SOCIETY OF COSMETIC CHEMISTS, 1993, 44 (03): : 153 - 162
  • [29] In-house Validation of the EpiOcular™ Eye Irritation Test and its Combination with the Bovine Corneal Opacity and Permeability Test for the Assessment of Ocular Irritation
    Kolle, Susanne N.
    Kandarova, Helena
    Wareing, Britta
    van Ravenzwaay, Bennard
    Landsiedel, Robert
    ATLA-ALTERNATIVES TO LABORATORY ANIMALS, 2011, 39 (04): : 365 - 387
  • [30] Relevance and reliability of the PREDISAFE assay in the COLIPA eye irritation validation program (Phase 1)
    Courtellemont, P
    Hébert, P
    Biesse, JP
    Castelli, D
    Friteau, L
    Serrano, J
    Robles, C
    TOXICOLOGY IN VITRO, 1999, 13 (02) : 305 - 312
12345