Evaluation of antibacterial, antifungal and modulatory activity of methanol and ethanol extracts of Padina sanctae-crucis

被引：8

作者：

Nogueira, Lavouisier F. B. ^{[1
]}

Morais, Edson C. ^{[1
]}

Brito, Maria A. D. ^{[1
]}

Santos, Beatriz S. ^{[1
]}

Vale, Doanny L. ^{[1
]}

Lucena, Bruno F. F. ^{[1
]}

Figueredo, Fernando G. ^{[1
]}

Guedes, Glaucia M. M. ^{[2
]}

Tintino, Saulo R. ^{[2
]}

Souza, Celestina E. S. ^{[2
]}

Nogueira, Raquel B. S. S. ^{[3
]}

Matias, Edinardo F. F. ^{[2
]}

Morais-Braga, Maria F. B. ^{[2
]}

Cunha, Emidio V. L. ^{[3
]}

Lima, Micheline A. ^{[3
]}

Coutinho, Henrique D. M. ^{[2
]}

机构：

[1] Doutor Leao Sampaio Coll, Fac Ciencias Aplicadas, Juazeiro do Norte, Ceara, Brazil

[2] Univ Reg Cariri, Dept Quim Biol, BR-63105000 Crato, Ceara, Brazil

[3] Univ Fed Paraiba, Lab Tecnol Farmaceut, BR-58059900 Joao Pessoa, Paraiba, Brazil

来源：

AFRICAN HEALTH SCIENCES | 2014年 / 14卷 / 02期

关键词：

multi-resistant microorganisms; modulation; Padina Sanctae-crucis; antimicrobial activity; RESISTANT STAPHYLOCOCCUS-AUREUS; ANTIBIOTIC-ACTIVITY; MEDICINAL-PLANTS; ENHANCEMENT; METHICILLIN; BRAZIL;

D O I：

10.4314/ahs.v14i2.12

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Multi-resistant microorganisms such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Candida tropicalis e Candida krusei are the main causes of microbial infections. Padina sanctae-crucis is a seaweed often used to check the contamination of ecosystems by materials such as heavy metals, but studies of the antimicrobial activity of the same seaweed were not found. Methods: The tests for the minimum inhibitory concentration and modulation of microbial resistance, with the use of ethanolic and methanolic extracts of Padina Sanctae-cruces combined with drugs of the class of aminoglycosides and antifungal were used to evaluate the activity against the cited microorganisms. Results: Was observed a modulation of antibiotic activity between the natural products and the E. coli and S. aureus strains, indicating a synergism and antagonism respectively. Conclusions: The results showed a moderate modulatory effect against some microorganisms studied.

引用

页码：372 / 376

页数：5

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