Long-chain omega 3 fatty acids: Molecular bases of potential antioxidant actions

被引:95
|
作者
Giordano, Elena [1 ]
Visioli, Francesco [1 ]
机构
[1] CEI UAM CSIC, Madrid Inst Adv Studies IMDEA Food, Lab Funct Foods, Madrid, Spain
关键词
Antioxidants; Polyunsaturated fatty acids; Free radicals; Cardiovascular disease; POLYUNSATURATED FATTY-ACIDS; FISH-OIL-RICH; OXIDATIVE STRESS; DOCOSAHEXAENOIC ACID; EICOSAPENTAENOIC ACID; POSTMENOPAUSAL WOMEN; LIPID-PEROXIDATION; SUPPLEMENTATION; OMEGA-3; OLEATE;
D O I
10.1016/j.plefa.2013.11.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several lines of investigation are being developed to assess the impact of polyunsaturated fatty acids, namely those of the omega 3 series, intake on oxidative stress. Keeping in mind that there might be a dose-response relation, in vivo and in vitro data strongly suggest that omega 3 fatty acids might act as anti- rather than pro-oxidant in several cells such as vascular cells, hence diminishing inflammation, oxidative stress, and, in turn, the risk of atherosclerosis and degenerative disorders such as cardiovascular disease. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1 / 4
页数:4
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