Several lines of investigation are being developed to assess the impact of polyunsaturated fatty acids, namely those of the omega 3 series, intake on oxidative stress. Keeping in mind that there might be a dose-response relation, in vivo and in vitro data strongly suggest that omega 3 fatty acids might act as anti- rather than pro-oxidant in several cells such as vascular cells, hence diminishing inflammation, oxidative stress, and, in turn, the risk of atherosclerosis and degenerative disorders such as cardiovascular disease. (C) 2013 Elsevier Ltd. All rights reserved.
机构:
Univ North Carolina Chapel Hill, Inst Nutr Res, Kannapolis, NC USA
Univ North Carolina Chapel Hill, Kannapolis, NC USAUniv North Carolina Chapel Hill, Inst Nutr Res, Kannapolis, NC USA
Cheatham, Carol L.
Sheppard, Kelly W.
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Univ North Carolina Chapel Hill, Inst Nutr Res, Kannapolis, NC USA
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Sheppard, Kelly W.
Lupu, Daniel S.
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Univ North Carolina Chapel Hill, Inst Nutr Res, Kannapolis, NC USA
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Lupu, Daniel S.
Niculescu, Mihai D.
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Univ North Carolina Chapel Hill, Inst Nutr Res, Kannapolis, NC USA
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