Long-chain omega 3 fatty acids: Molecular bases of potential antioxidant actions

被引:95
|
作者
Giordano, Elena [1 ]
Visioli, Francesco [1 ]
机构
[1] CEI UAM CSIC, Madrid Inst Adv Studies IMDEA Food, Lab Funct Foods, Madrid, Spain
关键词
Antioxidants; Polyunsaturated fatty acids; Free radicals; Cardiovascular disease; POLYUNSATURATED FATTY-ACIDS; FISH-OIL-RICH; OXIDATIVE STRESS; DOCOSAHEXAENOIC ACID; EICOSAPENTAENOIC ACID; POSTMENOPAUSAL WOMEN; LIPID-PEROXIDATION; SUPPLEMENTATION; OMEGA-3; OLEATE;
D O I
10.1016/j.plefa.2013.11.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several lines of investigation are being developed to assess the impact of polyunsaturated fatty acids, namely those of the omega 3 series, intake on oxidative stress. Keeping in mind that there might be a dose-response relation, in vivo and in vitro data strongly suggest that omega 3 fatty acids might act as anti- rather than pro-oxidant in several cells such as vascular cells, hence diminishing inflammation, oxidative stress, and, in turn, the risk of atherosclerosis and degenerative disorders such as cardiovascular disease. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1 / 4
页数:4
相关论文
共 50 条
  • [1] Bioavailability of long-chain omega-3 fatty acids
    Schuchardt, Jan Philipp
    Hahn, Andreas
    PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2013, 89 (01): : 1 - 8
  • [2] The therapeutic potential of long-chain omega-3 fatty acids in nonalcoholic fatty liver disease
    Shapiro, Haim
    Tehilla, Miryam
    Attal-Singer, Joelle
    Bruck, Rafael
    Luzzatti, Rachel
    Singer, Pierre
    CLINICAL NUTRITION, 2011, 30 (01) : 6 - 19
  • [3] Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids
    Wall, Rebecca
    Ross, R. Paul
    Fitzgerald, Gerald F.
    Stanton, Catherine
    NUTRITION REVIEWS, 2010, 68 (05) : 280 - 289
  • [4] Long-chain omega-3 fatty acids in red meat
    Howe, Peter
    Buckley, Jon
    Meyer, Barbara
    NUTRITION & DIETETICS, 2007, 64 : S135 - S139
  • [5] Cardiovascular disease and long-chain omega-3 fatty acids
    Harris, WS
    Park, Y
    Isley, WL
    CURRENT OPINION IN LIPIDOLOGY, 2003, 14 (01) : 9 - 14
  • [6] Long-Chain Omega-3 Fatty Acids and Blood Pressure
    Liu, James C.
    Conklin, Sarah M.
    Manuck, Stephen B.
    Yao, Jeffrey K.
    Muldoon, Matthew F.
    AMERICAN JOURNAL OF HYPERTENSION, 2011, 24 (10) : 1121 - 1126
  • [7] International recommendations for consumption of long-chain omega-3 fatty acids
    Harris, William S.
    JOURNAL OF CARDIOVASCULAR MEDICINE, 2007, 8 : S50 - S52
  • [8] Nutritional aspects of omega-3 long-chain polyunsaturated fatty acids
    Muggli, R
    AGRO FOOD INDUSTRY HI-TECH, 1997, 8 (01): : 35 - 36
  • [9] EFFECT OF LONG-CHAIN OMEGA-3-FATTY-ACIDS ON MITOCHONDRIAL BIOENERGETICS
    STILLWELL, W
    EHRINGER, WD
    CRUMP, T
    JENSKI, LJ
    BIOPHYSICAL JOURNAL, 1994, 66 (02) : A111 - A111
  • [10] Omega-3 long-chain polyunsaturated fatty acids and aquaculture in perspective
    Tocher, Douglas R.
    AQUACULTURE, 2015, 449 : 94 - 107