Synthesis and antiviral evaluation of pyridine fused heterocyclic and nucleosidic derivatives.

被引：5
|
作者：
Cobo, J
Sanchez, A
Nogueras, M
DeClercq, E
机构：
[1] UNIV JAEN,DEPT QUIM INORGAN & ORGAN,E-23071 JAEN,SPAIN
[2] CATHOLIC UNIV LEUVEN,REGA INST MED RES,B-3000 LOUVAIN,BELGIUM
来源：
TETRAHEDRON | 1997年 / 53卷 / 24期
关键词：
D O I：
10.1016/S0040-4020(97)00488-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Several 5-amino and 5-glycosylaminopyrrolo[3,4-c]pyridin-1,3(2H)-dione derivatives and 7-amino and 7-glycosylaminopyrido[3,4-d]pyridazin-1,3(2H,3H)-dione derivatives, were synthesized starting from 2-amino and 2-glycosylaminopyridines, respectively. For the preparation of pyrrolopyridine and pyridopyridazine derivatives we used ammonia and hydrazine monohydrate respectively. Those compounds were evaluated, but found inactive, for their invitro antiviral activity. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：8225 / 8236
页数：12
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