Frequency of silent myocardial ischemia in type 2 diabetic patients and the relation with poor glycemic control

被引:18
|
作者
Araz, M [1 ]
Celen, Z
Akdemir, I
Okan, V
机构
[1] Gaziantep Univ, Fac Med, Dept Internal Med, TR-27070 Gaziantep, Turkey
[2] Gaziantep Univ, Fac Med, Dept Nucl Med, Gaziantep, Turkey
[3] Gaziantep Univ, Fac Med, Dept Cardiol, Gaziantep, Turkey
关键词
silent myocardial ischemia; type 2 diabetes mellitus; HbA(1c); retinopathy;
D O I
10.1007/s00592-004-0142-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aim of the study was to investigate the frequency of silent myocardial ischemia in type 2 diabetic patients without any clinical or laboratory findings of myocardial ischemia and to examine the related factors for silent myocardial ischemia. A total of 116 type 2 diabetic patients (82 women) with a disease duration of 5-20 years were included in the study. All patients underwent stress and resting myocardial perfusion single-photon emission computed tomographic (SPECT) study with Tc-99m-MIBI. Coronary angiography was performed in patients with ischemia established at myocardial perfusion SPECT. Ischemia was determined in 18 (15.5%) patients by myocardial perfusion SPECT. Coronary angiography performed in 17 of these patients confirmed coronary stenosis >50% in 11 patients. Thus, the prevalence of silent myocardial ischemia was 9.6%. Significant relations were found between silent myocardial ischemia and male sex, high HbA(1C) level and retinopathy. Type 2 diabetic patients (especially men) with poorly controlled diabetes mellitus or retinopathy should be screened for silent myocardial ischemia.
引用
收藏
页码:38 / 43
页数:6
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