Anti-cancer Activity and Docking Studies of Pyran Derivatives

被引：0
|
作者：
Yu, Xuejun [1 ]
机构：
[1] Zhejiang Canc Hosp, Dept Anesthesia, Hangzhou 310022, Zhejiang, Peoples R China
来源：
LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 07期
关键词：
cancer cell; molecular docking; pyran; X-ray;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The synthesis and characterization of two novel pyran derivatives (1 and 2) were realized by means of IR, 1H NMR, HRMS and single crystal X-ray crystallography. The anticancer activity of the two compounds were investigated against four human cancer cell lines (GES-1, SGC-7901, BGC-823 and MGC-803) by MTT assay. In addition, the relationship between activity and structure of the two compounds was further investigated through molecular docking study.
引用
收藏
页码：1315 / 1319
页数：5
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