Application of self-assembly techniques in the design of biocompatible protein microarray surfaces

被引：2
|
作者：
Schaeferling, M
Schiller, S
Paul, H
Kruschina, M
Pavlickova, P
Meerkamp, M
Giammasi, C
Kambhampati, D
机构：
[1] Xom Surface Technol, D-89077 Ulm, Germany
[2] Univ Regensburg, Inst Analyt Chem Chemo & Biosensors, D-8400 Regensburg, Germany
[3] Max Planck Inst Polymer Res, Mainz, Germany
[4] Thermo Hybaid GmbH, Ulm, Germany
来源：
ELECTROPHORESIS | 2002年 / 23卷 / 18期
关键词：
protein microarrays; proteomics; review; self-assembled monolayers;
D O I：
10.1002/1522-2683(200209)23:18<3097::AID-ELPS3097>3.0.CO;2-G
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
This review focuses on the application of novel technologies for generating biocompatible surfaces for high-throughput screening (HTS) of proteins. Various methods of coupling and spotting proteins on self-assembled monolayer (SAM) surfaces will be described along with the protein chip challenges pertaining to spot homogeneity, morphology, biocompatibility and reproducibility.
引用
收藏
页码：3097 / 3105
页数：9
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