Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis

被引：31

作者：

Wajchenberg, Bernardo Leo ^{[1
,2
]}

Nery, Marcia ^{[1
,2
]}

Cunha, Maria Rosaria ^{[1
,2
]}

Rossi da Silva, Maria Elizabeth ^{[1
,2
]}

机构：

[1] HC FMUSP, Serv Endocrinol, Sao Paulo, Brazil

[2] HC FMUSP, InsCor, Ctr Diabet Coracao, Sao Paulo, Brazil

来源：

ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA | 2009年 / 53卷 / 02期

关键词：

Obesity; visceral and subcutaneous adipose tissue; low grade inflammation; atherosclerosis; metabolic syndrome; C-REACTIVE PROTEIN; INSULIN-RESISTANCE; OBESE WOMEN; DISEASE; ACTIVATION; STRESS; ORGAN; RISK;

D O I：

10.1590/S0004-27302009000200005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The authors analyze insulin resistance, the metabolic syndrome and endothelial dysfunction as consequence of a common antecedent, a low grade inflammation, indicating that in obesity there is a chronically activated inflammatory state of the adipose tissue. Furthermore, the inflammatory signaling is discussed according to the adipose tissue depot, visceral or subcutaneous. Arq Bras Endocrino: Metab. 2009;53(2):145-150.

引用

页码：145 / 150

页数：6

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