Recent progress on asymmetric organocatalytic construction of chiral cyclohexenone skeletons

被引：55
|
作者：
Yang, Xin [1 ]
Wang, Jun [1 ]
Li, Pengfei [1 ]
机构：
[1] South Univ Sci & Technol China, Dept Chem, Shenzhen, Guangdong, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 16期
基金：
中国国家自然科学基金;
关键词：
OPTICALLY-ACTIVE 5-(TERT-BUTYLDIMETHYLSILOXY)-2-CYCLOHEXENONE; INTRAMOLECULAR STETTER REACTION; WIELAND-MIESCHER KETONE; SAUER-WIECHERT REACTION; DOMINO MICHAEL-ALDOL; ALPHA; BETA-UNSATURATED KETONES; ROBINSON ANNULATION; BUILDING-BLOCKS; PRIMARY-AMINE; ENANTIOSELECTIVE SYNTHESIS;
D O I：
10.1039/c3ob42293c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Chiral cyclohex-2-enones are important building blocks in synthetic chemistry and the life science industries and much attention has been drawn to the development of efficient and practical methodologies for accessing these enantio-enriched cyclohex-2-enone skeletons. This review describes the impressive progress that has been made in terms of employing new methodologies, suitable reactants as well as more efficient catalyst systems for this important enantioselective transformation. Also, the reaction mechanisms are briefly discussed.
引用
收藏
页码：2499 / 2513
页数：15
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